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231225s2020 xx |||||o 00| ||eng c |
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|a 10.1021/acs.langmuir.0c01360
|2 doi
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|a pubmed24n1360.xml
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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| 100 |
1 |
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|a Lee, Jing J
|e verfasserin
|4 aut
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| 245 |
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|a Open-Channel Capillary Trees and Capillary Pumping
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| 264 |
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|c 2020
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| 336 |
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
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|2 rdacarrier
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|a Date Completed 21.06.2021
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|a Date Revised 02.04.2024
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a Velocity of capillary flow in closed or open channels decreases as the flow proceeds down the length of the channel, varying as the inverse of the square root of time or as the inverse of travel distance. In order to increase the flow rate-and extend the duration of the flow-capillary pumps have been designed by mimicking the pumping principle of paper or cotton fibers. These designs provide a larger volume available for the wicking of the liquids. In microsystems for biotechnology, different designs have been developed based on experimental observation. In the present paper, the mechanisms at the basis of capillary pumping are investigated using a theoretical model for the flow in an open-channel "capillary tree" (i.e., an ensemble of channels with bifurcations mimicking the shape of a tree). The model is checked against experiments. Rules for obtaining better designs of capillary pumps are proposed; specifically, we find (1) when using a capillary tree with identical channel cross-sectional areas throughout, it is possible to maintain nearly constant flow rates throughout the channel network, (2) flow rate can be increased at each branch point of a capillary tree by slightly decreasing the areas of the channel cross section and decreasing the channel lengths at each level of ramification within the tree, and (3) higher order branching (trifurcations vs bifurcations) amplify the flow rate effect. This work lays the foundation for increasing the flow rate in open microfluidic channels driven by capillary flow; we expect this to have broad impact across open microfluidics for biological and chemical applications such as cell culture, sample preparation, separations, and on-chip reactions
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|a Journal Article
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|a Research Support, N.I.H., Extramural
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| 650 |
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|a Research Support, Non-U.S. Gov't
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| 700 |
1 |
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|a Berthier, Jean
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Kearney, Kathleen E
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Berthier, Erwin
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Theberge, Ashleigh B
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1999
|g 36(2020), 43 vom: 03. Nov., Seite 12795-12803
|w (DE-627)NLM098181009
|x 1520-5827
|7 nnns
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| 773 |
1 |
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|g volume:36
|g year:2020
|g number:43
|g day:03
|g month:11
|g pages:12795-12803
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| 856 |
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|u http://dx.doi.org/10.1021/acs.langmuir.0c01360
|3 Volltext
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