2D and 3D in vitro assays to quantify the invasive behavior of glioblastoma stem cells in response to SDF-1α
Invasion is a hallmark of cancer and therefore in vitro invasion assays are important tools in cancer research. We aimed to describe in vitro 2D transwell assays and 3D spheroid assays to quantitatively determine the invasive behavior of glioblastoma stem cells in response to the chemoattractant SDF...
Ausführliche Beschreibung
Bibliographische Detailangaben
| Veröffentlicht in: | BioTechniques. - 1988. - 69(2020), 5 vom: 03. Nov., Seite 339-346
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| 1. Verfasser: |
Hira, Vashendriya Vv
(VerfasserIn) |
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| Weitere Verfasser: |
Breznik, Barbara,
Van Noorden, Cornelis Jf,
Lah, Tamara,
Molenaar, Remco J |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2020
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| Zugriff auf das übergeordnete Werk: | BioTechniques
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| Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
2D transwell invasion assay
3D spheroid invasion assay
cancer cell
cellular invasion
glioblastoma stem cells
CXCR4 protein, human
Chemokine CXCL12
Drug Combinations
mehr...
Laminin
Proteoglycans
Receptors, CXCR4
matrigel
119978-18-6
Collagen
9007-34-5 |
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