A Quantitative Bacteria Monitoring and Killing Platform Based on Electron Transfer from Bacteria to a Semiconductor

A Quantitative Bacteria Monitoring and Killing Platform Based on Electron Transfer from Bacteria to a Semiconductor

© 2020 Wiley-VCH GmbH.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 32(2020), 39 vom: 03. Okt., Seite e2003616
1. Verfasser: Wang, Guomin (VerfasserIn)
Weitere Verfasser: Tang, Kaiwei, Meng, Zheyi, Liu, Pei, Mo, Shi, Mehrjou, Babak, Wang, Huaiyu, Liu, Xuanyong, Wu, Zhengwei, Chu, Paul K
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2020
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article Au nanoparticles antibacterial activity bacteria sensing electron transfer zinc oxide nanorods
Beschreibung
Zusammenfassung:© 2020 Wiley-VCH GmbH.
A platform with both bacteria killing and sensing capabilities is crucial for monitoring the entire bacteria-related process on biomaterials and biomedical devices. Electron transfer (ET) between the bacteria and a Au-loaded semiconductor (ZnO) is observed to be the primary factor for effective bacteria sensing and fast bacteria killing. The electrons produce a saturation current that varies linearly with the bacteria number, semi-logarithmically, with R2 of 0.98825, thus providing an excellent tool to count bacteria quantitatively in real-time. Furthermore, ET leads to continuous electron loss killing of about 80% of Escherichia coli in only 1 h without light. The modularity and extendability of this ET-based platform are also demonstrated by the excellent results obtained from other semiconductor/substrate systems and the stability is confirmed by recycling tests. The underlying mechanism for the dual functions is not due to conventional attributed Zn2+ leaching or photocatalysis but instead electrical interactions upon direct contact. The results reveal the capability of real-time detection of bacteria based on ET while providing information about the antibacterial behavior of ZnO-based materials especially in the early stage. The concept can be readily incorporated into the design of smart and miniaturized devices that can sense and kill bacteria simultaneously
Beschreibung:Date Completed 11.08.2021
Date Revised 11.08.2021
published: Print-Electronic
Citation Status MEDLINE
ISSN:1521-4095
DOI:10.1002/adma.202003616