|
|
|
|
| LEADER |
01000naa a22002652 4500 |
| 001 |
NLM313113602 |
| 003 |
DE-627 |
| 005 |
20231225145853.0 |
| 007 |
cr uuu---uuuuu |
| 008 |
231225s2020 xx |||||o 00| ||eng c |
| 024 |
7 |
|
|a 10.1016/j.clim.2020.108548
|2 doi
|
| 028 |
5 |
2 |
|a pubmed24n1043.xml
|
| 035 |
|
|
|a (DE-627)NLM313113602
|
| 035 |
|
|
|a (NLM)32735869
|
| 035 |
|
|
|a (PII)S1521-6616(20)30285-0
|
| 040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
| 041 |
|
|
|a eng
|
| 100 |
1 |
|
|a Shen, Ching-Fen
|e verfasserin
|4 aut
|
| 245 |
1 |
4 |
|a The cellular immunophenotype expression of influenza A virus and influenza B virus infection in children
|
| 264 |
|
1 |
|c 2020
|
| 336 |
|
|
|a Text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a ƒaComputermedien
|b c
|2 rdamedia
|
| 338 |
|
|
|a ƒa Online-Ressource
|b cr
|2 rdacarrier
|
| 500 |
|
|
|a Date Completed 17.05.2021
|
| 500 |
|
|
|a Date Revised 17.05.2021
|
| 500 |
|
|
|a published: Print-Electronic
|
| 500 |
|
|
|a Citation Status MEDLINE
|
| 520 |
|
|
|a Copyright © 2020 Elsevier Inc. All rights reserved.
|
| 520 |
|
|
|a BACKGROUND: The innate immune response is the primary defense against influenza virus infection
|
| 520 |
|
|
|a METHODS: This is a prospective study carried out in children <18 years of age who were diagnosed with influenza A or influenza B infection. Demographic and clinical data, laboratory findings and cell immunophenotypes on first presentation were compared
|
| 520 |
|
|
|a RESULTS: With respect to immunophenotype, influenza A infection resulted in a higher fraction of CD14+ and CD4+IL-17A+cells compared to children infected with influenza B. By contrast, influenza B infection resulted in a comparatively higher percentage of double-negative CD4-CD8- lymphocyte subsets. Influenza A infection was associated with comparatively higher percentages of CD4+CD25highFoxp3+ and CD4+CD25lowFoxp3+ cells. By contrast, the percentage of CD8+CD25high and CD8+CD25low cells was similar among patients with influenza A infection and influenza B infection
|
| 520 |
|
|
|a CONCLUSIONS: An improved understanding of the fraction of regulatory T cells with influenza virus infections may provide further understandings on immune responses
|
| 650 |
|
4 |
|a Comparative Study
|
| 650 |
|
4 |
|a Journal Article
|
| 650 |
|
4 |
|a Observational Study
|
| 650 |
|
4 |
|a Antivirals
|
| 650 |
|
4 |
|a CD25
|
| 650 |
|
4 |
|a Immunophenotype
|
| 650 |
|
4 |
|a Influenza virus
|
| 650 |
|
4 |
|a Treg
|
| 700 |
1 |
|
|a Ho, Tzong-Shiann
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Wang, Shih-Min
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Liao, Yu-Ting
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Hu, Yu-Shiang
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Tsai, Huey-Pin
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Chen, Shun-Hua
|e verfasserin
|4 aut
|
| 773 |
0 |
8 |
|i Enthalten in
|t Clinical immunology (Orlando, Fla.)
|d 1999
|g 219(2020) vom: 30. Okt., Seite 108548
|w (DE-627)NLM098196855
|x 1521-7035
|7 nnns
|
| 773 |
1 |
8 |
|g volume:219
|g year:2020
|g day:30
|g month:10
|g pages:108548
|
| 856 |
4 |
0 |
|u http://dx.doi.org/10.1016/j.clim.2020.108548
|3 Volltext
|
| 912 |
|
|
|a GBV_USEFLAG_A
|
| 912 |
|
|
|a SYSFLAG_A
|
| 912 |
|
|
|a GBV_NLM
|
| 912 |
|
|
|a GBV_ILN_11
|
| 912 |
|
|
|a GBV_ILN_24
|
| 912 |
|
|
|a GBV_ILN_350
|
| 951 |
|
|
|a AR
|
| 952 |
|
|
|d 219
|j 2020
|b 30
|c 10
|h 108548
|