qtl2pleio : Testing pleiotropy vs. separate QTL in multiparental populations
Modern quantitative trait locus (QTL) studies in multiparental populations offer opportunities to identify causal genes for thousands of clinical and molecular traits. Traditional analyses examine each trait by itself. However, to fully leverage this vast number of measured traits, the systems genet...
| Veröffentlicht in: | Journal of open source software. - 2017. - 4(2019), 38 vom: 01. |
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| Format: | Online-Aufsatz |
| Sprache: | English |
| Veröffentlicht: |
2019
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| Zugriff auf das übergeordnete Werk: | Journal of open source software |
| Schlagworte: | Journal Article |
| Zusammenfassung: | Modern quantitative trait locus (QTL) studies in multiparental populations offer opportunities to identify causal genes for thousands of clinical and molecular traits. Traditional analyses examine each trait by itself. However, to fully leverage this vast number of measured traits, the systems genetics community needs statistical tools to analyze multiple traits simultaneously (Jiang & Zeng, 1995; Korol, Ronin, & Kirzhner, 1995). A test of pleiotropy vs. separate QTL is one such tool that will aid dissection of complex trait genetics and enhance understanding of genetic architecture |
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| Beschreibung: | Date Revised 28.09.2020 published: Print-Electronic Citation Status PubMed-not-MEDLINE |
| ISSN: | 2475-9066 |
| DOI: | 10.21105/joss.01435 |