Shielded Silver Nanorods for Bioapplications

Copyright © 2020 American Chemical Society.

Bibliographische Detailangaben
Veröffentlicht in:Chemistry of materials : a publication of the American Chemical Society. - 1998. - 32(2020), 13 vom: 14. Juli, Seite 5879-5889
1. Verfasser: Zhuo, Xiaolu (VerfasserIn)
Weitere Verfasser: Henriksen-Lacey, Malou, Jimenez de Aberasturi, Dorleta, Sánchez-Iglesias, Ana, Liz-Marzán, Luis M
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2020
Zugriff auf das übergeordnete Werk:Chemistry of materials : a publication of the American Chemical Society
Schlagworte:Journal Article
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520 |a Silver is arguably the best plasmonic material in terms of optical performance. However, wide application of Ag and Ag-containing nanoparticles is usually hindered by two major drawbacks, namely, chemical degradation and cytotoxicity. We report herein a synthetic method for highly monodisperse polymer-coated Ag nanorods, which are thereby protected against external stimuli (oxidation, light, heat) and are noncytotoxic to various cell lines. The monodispersity of Ag nanorods endows them with narrow plasmon bands, which are tunable into the near-infrared biological transparency window, thus facilitating application in bioanalytical and therapeutic techniques. We demonstrate intracellular surface-enhanced Raman scattering (SERS) imaging using Ag nanorods encoded with five different Raman reporter molecules. Encoded Ag nanorods display long-term stability in terms of size, shape, optical response, and SERS signal. Our results help eliminate concerns of instability and cytotoxicity in the application of Ag-containing nanoparticles with enhanced optical response, toward the development of bioapplications 
650 4 |a Journal Article 
700 1 |a Henriksen-Lacey, Malou  |e verfasserin  |4 aut 
700 1 |a Jimenez de Aberasturi, Dorleta  |e verfasserin  |4 aut 
700 1 |a Sánchez-Iglesias, Ana  |e verfasserin  |4 aut 
700 1 |a Liz-Marzán, Luis M  |e verfasserin  |4 aut 
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