Dual-Threshold Time-over-Threshold Nonlinearity Correction for PET Detectors

The Time-over-Threshold (ToT) analog-to-digital signal processing approach provides a power-efficient and cost-effective technique to extract all relevant information from detectors in high-energy physics and Positron Emission Tomography (PET) imaging. In this work, three calibration methods were in...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment. - 1987. - 971(2020) vom: 11. Aug.
1. Verfasser: Gaudin, Émilie (VerfasserIn)
Weitere Verfasser: Thibaudeau, Christian, Arpin, Louis, Bouziri, Haithem, Fontaine, Réjean, Lecomte, Roger
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2020
Zugriff auf das übergeordnete Werk:Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment
Schlagworte:Journal Article Time-over-threshold avalanche photodiodes positron emission tomography
LEADER 01000caa a22002652c 4500
001 NLM312023324
003 DE-627
005 20250227131723.0
007 cr uuu---uuuuu
008 231225s2020 xx |||||o 00| ||eng c
024 7 |a 10.1016/j.nima.2020.164100  |2 doi 
028 5 2 |a pubmed25n1039.xml 
035 |a (DE-627)NLM312023324 
035 |a (NLM)32624634 
035 |a (PII)164100 
040 |a DE-627  |b ger  |c DE-627  |e rakwb 
041 |a eng 
100 1 |a Gaudin, Émilie  |e verfasserin  |4 aut 
245 1 0 |a Dual-Threshold Time-over-Threshold Nonlinearity Correction for PET Detectors 
264 1 |c 2020 
336 |a Text  |b txt  |2 rdacontent 
337 |a ƒaComputermedien  |b c  |2 rdamedia 
338 |a ƒa Online-Ressource  |b cr  |2 rdacarrier 
500 |a Date Revised 11.08.2020 
500 |a published: Print-Electronic 
500 |a Citation Status PubMed-not-MEDLINE 
520 |a The Time-over-Threshold (ToT) analog-to-digital signal processing approach provides a power-efficient and cost-effective technique to extract all relevant information from detectors in high-energy physics and Positron Emission Tomography (PET) imaging. In this work, three calibration methods were investigated to correct the inherent nonlinear response of the ToT data using 1) γ-ray sources of various energies, 2) internal electronic gain variation in the LabPET II ASIC in combination with a single energy γ-ray source, and 3) internal gain variation along with an embedded pulse charge generator in replacement of a γ-ray source. The electronic gain calibration technique was shown to achieve equivalent correction accuracy as the γ-ray sources calibration. Furthermore, this method has the advantage of allowing a faster calibration requiring only one single γ-ray source (e.g., 511 keV) and a quick automated routine to sweep the internal gain. The last technique would be the most convenient method, provided that the signal pulse shape would be similar to the detector signal responding to a typical γ-ray event. Whereas the concept was demonstrated with a step pulse, extensive processing would be required to recover the nonlinearity correction factors for the detector pulse shape. After calibration, the 511-keV energy resolution of typical LabPET II detectors was only slightly degraded, by less than 12% and 8% for methods 1) and 2), respectively, relative to a conventional ADC-based data acquisition system. The feasibility of fast and accurate calibration for the nonlinearity correction of ToT data in PET imaging was demonstrated, making a daily quality control within reach 
650 4 |a Journal Article 
650 4 |a Time-over-threshold 
650 4 |a avalanche photodiodes 
650 4 |a positron emission tomography 
700 1 |a Thibaudeau, Christian  |e verfasserin  |4 aut 
700 1 |a Arpin, Louis  |e verfasserin  |4 aut 
700 1 |a Bouziri, Haithem  |e verfasserin  |4 aut 
700 1 |a Fontaine, Réjean  |e verfasserin  |4 aut 
700 1 |a Lecomte, Roger  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment  |d 1987  |g 971(2020) vom: 11. Aug.  |w (DE-627)NLM098171771  |x 0168-9002  |7 nnas 
773 1 8 |g volume:971  |g year:2020  |g day:11  |g month:08 
856 4 0 |u http://dx.doi.org/10.1016/j.nima.2020.164100  |3 Volltext 
912 |a GBV_USEFLAG_A 
912 |a SYSFLAG_A 
912 |a GBV_NLM 
912 |a GBV_ILN_350 
951 |a AR 
952 |d 971  |j 2020  |b 11  |c 08