|
|
|
|
| LEADER |
01000naa a22002652 4500 |
| 001 |
NLM310860121 |
| 003 |
DE-627 |
| 005 |
20231225141017.0 |
| 007 |
cr uuu---uuuuu |
| 008 |
231225s2020 xx |||||o 00| ||eng c |
| 024 |
7 |
|
|a 10.1111/nph.16725
|2 doi
|
| 028 |
5 |
2 |
|a pubmed24n1036.xml
|
| 035 |
|
|
|a (DE-627)NLM310860121
|
| 035 |
|
|
|a (NLM)32506490
|
| 040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
| 041 |
|
|
|a eng
|
| 100 |
1 |
|
|a Rutter, Brian D
|e verfasserin
|4 aut
|
| 245 |
1 |
0 |
|a Growing pains
|b addressing the pitfalls of plant extracellular vesicle research
|
| 264 |
|
1 |
|c 2020
|
| 336 |
|
|
|a Text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a ƒaComputermedien
|b c
|2 rdamedia
|
| 338 |
|
|
|a ƒa Online-Ressource
|b cr
|2 rdacarrier
|
| 500 |
|
|
|a Date Completed 26.04.2021
|
| 500 |
|
|
|a Date Revised 26.04.2021
|
| 500 |
|
|
|a published: Print-Electronic
|
| 500 |
|
|
|a Citation Status MEDLINE
|
| 520 |
|
|
|a © 2020 The Authors. New Phytologist © 2020 New Phytologist Trust.
|
| 520 |
|
|
|a Extracellular vesicles (EVs) are small, membrane-enclosed compartments that mediate the intercellular transport of proteins and small RNAs. In plants, EVs are thought to play a prominent role in immune responses and are being championed as the long-sought-after mechanism for host-induced gene silencing. However, parallel research on mammalian EVs is raising concerns about potential pitfalls faced by all EV researchers that will need to be addressed in order to convincingly establish that EVs are the primary mediators of small RNA transfer between organisms. Here we discuss these pitfalls in the context of plant EV research, with a focus on experimental approaches required to distinguish bona fide EV cargo from merely co-purifying contaminants
|
| 650 |
|
4 |
|a Journal Article
|
| 650 |
|
4 |
|a Research Support, Non-U.S. Gov't
|
| 650 |
|
4 |
|a Research Support, U.S. Gov't, Non-P.H.S.
|
| 650 |
|
4 |
|a Review
|
| 650 |
|
4 |
|a HIGS
|
| 650 |
|
4 |
|a extracellular vesicles (EVs)
|
| 650 |
|
4 |
|a host-induced gene silencing
|
| 650 |
|
4 |
|a miRNA
|
| 650 |
|
4 |
|a plant
|
| 650 |
|
4 |
|a sRNA
|
| 650 |
|
4 |
|a trans-kingdom gene silencing
|
| 650 |
|
7 |
|a RNA
|2 NLM
|
| 650 |
|
7 |
|a 63231-63-0
|2 NLM
|
| 700 |
1 |
|
|a Innes, Roger W
|e verfasserin
|4 aut
|
| 773 |
0 |
8 |
|i Enthalten in
|t The New phytologist
|d 1979
|g 228(2020), 5 vom: 15. Dez., Seite 1505-1510
|w (DE-627)NLM09818248X
|x 1469-8137
|7 nnns
|
| 773 |
1 |
8 |
|g volume:228
|g year:2020
|g number:5
|g day:15
|g month:12
|g pages:1505-1510
|
| 856 |
4 |
0 |
|u http://dx.doi.org/10.1111/nph.16725
|3 Volltext
|
| 912 |
|
|
|a GBV_USEFLAG_A
|
| 912 |
|
|
|a SYSFLAG_A
|
| 912 |
|
|
|a GBV_NLM
|
| 912 |
|
|
|a GBV_ILN_350
|
| 951 |
|
|
|a AR
|
| 952 |
|
|
|d 228
|j 2020
|e 5
|b 15
|c 12
|h 1505-1510
|