Discovery of alliin as a putative inhibitor of the main protease of SARS-CoV-2 by molecular docking

The outbreak of viral pneumonia caused by the novel coronavirus SARS-CoV-2 that began in December 2019 caused high mortality. It has been suggested that the main protease (Mpro) of SARS-CoV-2 may be an important target to discover pharmaceutical compounds for the therapy of this life-threatening dis...

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Publié dans:BioTechniques. - 1993. - 69(2020), 2 vom: 22. Aug., Seite 108-112
Auteur principal: Cheng, Bijun (Auteur)
Autres auteurs: Li, Tianjiao
Format: Article en ligne
Langue:English
Publié: 2020
Accès à la collection:BioTechniques
Sujets:Journal Article Research Support, Non-U.S. Gov't SARS-CoV-2 Mpro alliin molecular docking remdesivir ritonavir Antimalarials Antiviral Agents Viral Nonstructural Proteins plus... 3QKI37EEHE Adenosine Monophosphate 415SHH325A 7I4L2D0E9G Chloroquine 886U3H6UFF Cysteine Endopeptidases EC 3.4.22.- Coronavirus 3C Proteases EC 3.4.22.28 Cysteine K848JZ4886 Ritonavir O3J8G9O825 Alanine OF5P57N2ZX