Arabidopsis NUCLEAR FACTOR Y A8 inhibits the juvenile-to-adult transition by activating transcription of MIR156s

© The Author(s) 2020. Published by Oxford University Press on behalf of the Society for Experimental Biology. All rights reserved. For permissions, please email: journals.permissionsoup.com.

Bibliographische Detailangaben
Veröffentlicht in:Journal of experimental botany. - 1985. - 71(2020), 16 vom: 06. Aug., Seite 4890-4902
1. Verfasser: Zhao, Hang (VerfasserIn)
Weitere Verfasser: Lin, Ke, Ma, Lin, Chen, Qingshuai, Gan, Shuo, Li, Gang
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2020
Zugriff auf das übergeordnete Werk:Journal of experimental botany
Schlagworte:Journal Article Research Support, Non-U.S. Gov't NF-YA8 Flowering juvenile-to-adult transition miR156 phase changes Arabidopsis Proteins CCAAT-Binding Factor MicroRNAs mehr... Mirn156 microRNA, Arabidopsis nuclear factor Y
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520 |a © The Author(s) 2020. Published by Oxford University Press on behalf of the Society for Experimental Biology. All rights reserved. For permissions, please email: journals.permissionsoup.com. 
520 |a Vegetative (juvenile-to-adult) and flowering (vegetative-to-reproductive) phase changes are crucial in the life cycle of higher plants. MicroRNA156 (miR156) and its target SQUAMOSA PROMOTER BINDING PROTEIN-LIKE (SPL) genes are master regulators that determine vegetative phase changes. The miR156 level gradually declines as a plant ages and its expression is rapidly repressed by sugar. However, the underlying regulatory mechanism of transcriptional regulation of the MIR156 gene remains largely unknown. In this study, we demonstrated that Arabidopsis NUCLEAR FACTOR Y A8 (NF-YA8) binds directly to CCAAT cis-elements in the promoters of multiple MIR156 genes, thus activating their transcription and inhibiting the juvenile-to-adult transition. NF-YA8 was highly expressed in juvenile-stage leaves, and significantly repressed with developmental age and by sugar signals. Our results suggest that NF-YA8 acts as a signaling hub, integrating internal developmental age and sugar signals to regulate the transcription of MIR156s, thus affecting the juvenile-to-adult and flowering transitions 
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650 4 |a NF-YA8 
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650 4 |a juvenile-to-adult transition 
650 4 |a miR156 
650 4 |a phase changes 
650 7 |a Arabidopsis Proteins  |2 NLM 
650 7 |a CCAAT-Binding Factor  |2 NLM 
650 7 |a MicroRNAs  |2 NLM 
650 7 |a Mirn156 microRNA, Arabidopsis  |2 NLM 
650 7 |a nuclear factor Y  |2 NLM 
700 1 |a Lin, Ke  |e verfasserin  |4 aut 
700 1 |a Ma, Lin  |e verfasserin  |4 aut 
700 1 |a Chen, Qingshuai  |e verfasserin  |4 aut 
700 1 |a Gan, Shuo  |e verfasserin  |4 aut 
700 1 |a Li, Gang  |e verfasserin  |4 aut 
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