Characterization of the Spatial Organization of Raf Isoforms Interacting with K-Ras4B in the Lipid Membrane

Activation of Raf kinases by the membrane-anchored protein K-Ras4B is a key step of cellular signal regulation. As a predominant variant of the Ras family, K-Ras4B has been considered to be a major drug target in cancer therapy. Therefore, an integrated study of Raf interaction with membrane-associa...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 36(2020), 21 vom: 02. Juni, Seite 5944-5953
1. Verfasser: Li, Lei (VerfasserIn)
Weitere Verfasser: Möbitz, Simone, Winter, Roland
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2020
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Lipids Protein Isoforms