Short-range regulatory chromatin loops in plants

© 2020 The Authors. New Phytologist © 2020 New Phytologist Trust.

Bibliographische Detailangaben
Veröffentlicht in:The New phytologist. - 1979. - 228(2020), 2 vom: 01. Okt., Seite 466-471
1. Verfasser: Gagliardi, Delfina (VerfasserIn)
Weitere Verfasser: Manavella, Pablo A
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2020
Zugriff auf das übergeordnete Werk:The New phytologist
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Review DNA methylation chromatin loops chromatin structure genome topology short-range chromatin interactions small RNAs Chromatin Heterochromatin
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520 |a In all eukaryotic organisms, gene expression correlates with the condensation state of the chromatin. Highly packed genome regions, known as heterochromatins, are associated with repressed loci, whereas euchromatic regions represent a relaxed state of the chromatin actively transcribed. However, even in these active regions, associations between chromatin domains dynamically modify genome topology and alter gene expression. Long-range interaction within and between chromosomes determines chromatin domains that help to coordinate transcriptional events. On the other hand, short-range chromatin interactions emerged as dynamic mechanisms regulating the expression of specific loci. Our current capacity to decipher genome topology at high resolution allowed us to identify numerous cases of short-range regulatory chromatin interactions, which are reviewed in this Insight article 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
650 4 |a Review 
650 4 |a DNA methylation 
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650 4 |a genome topology 
650 4 |a short-range chromatin interactions 
650 4 |a small RNAs 
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