Anti-Vascular Endothelial Growth Factor Therapy for Radiation Retinopathy
Copyright 2020, SLACK Incorporated.
Veröffentlicht in: | Ophthalmic surgery, lasers & imaging retina. - 2013. - 51(2020), 4 vom: 01. Apr., Seite S44-S49 |
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Format: | Online-Aufsatz |
Sprache: | English |
Veröffentlicht: |
2020
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Zugriff auf das übergeordnete Werk: | Ophthalmic surgery, lasers & imaging retina |
Schlagworte: | Journal Article Review Angiogenesis Inhibitors Vascular Endothelial Growth Factor A |
Zusammenfassung: | Copyright 2020, SLACK Incorporated. BACKGROUND AND OBJECTIVE: The purpose of this article is to review the role of anti-vascular endothelial growth factor (VEGF) therapy in treating patients with radiation retinopathy (RR) PATIENTS AND METHODS: RR can be associated with a significant decrease in visual acuity (VA) related to the development of cystoid macular edema, macular ischemia, and proliferative retinopathy leading to neovascular glaucoma RESULTS: Anti-VEGF therapy is effective at stabilizing VA in around 80% of patients and achieving reductions in central macular thickness when it is administered using a constant algorithm. Furthermore, consistent prophylactic anti-VEGF therapy reduces the risk of development of RR, neovascularization of the iris, and neovascularization glaucoma CONCLUSION: Future studies are needed to determine the optimal regimen for anti-VEGF therapy according to patient risk factors and likelihood of developing RR. [Ophthalmic Surg Lasers Imaging Retina. 2020;51:S44-S49.] |
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Beschreibung: | Date Completed 14.04.2021 Date Revised 14.04.2021 published: Print Citation Status MEDLINE |
ISSN: | 2325-8179 |
DOI: | 10.3928/23258160-20200401-06 |