Use of OCTA Capillary Perfusion Density Measurements to Detect and Grade Macular Ischemia

Bibliographische Detailangaben
Veröffentlicht in:	Ophthalmic surgery, lasers & imaging retina. - 2013. - 51(2020), 4 vom: 01. Apr., Seite S30-S36
1. Verfasser:	Babiuch, Amy S (VerfasserIn)
Weitere Verfasser:	Uchida, Atsuro, Hu, Ming, Khan, Mehnaz, Srivastava, Sunil K, Singh, Rishi P, Kaiser, Peter K, Rachtiskaya, Aleksandra, Reese, Jamie L, Ehlers, Justis P
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2020
Zugriff auf das übergeordnete Werk:	Ophthalmic surgery, lasers & imaging retina
Schlagworte:	Comparative Study Journal Article Observational Study Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Beschreibung
Zusammenfassung:	Copyright 2020, SLACK Incorporated. BACKGROUND AND OBJECTIVE: To compare optical coherence tomography angiography (OCTA) capillary perfusion density (CPD) measurements of normal eyes and eyes with macular ischemia (MI) PATIENTS AND METHODS: AVATAR is an institutional review board-approved, prospective, observational imaging study using the Avanti RTVue XR HD. OCTA reports were reviewed for the presence of MI. Qualitative MI grading was performed, and CPD metrics in the superficial and deep fovea and parafovea were analyzed. A normal eye cohort was identified for comparative assessment RESULTS: The MI and normal cohorts included 55 and 58 eyes, respectively. Compared to normal eyes, eyes with MI had significantly lower CPD values in all regions. There was a statistically significant correlation between qualitative MI grade and VA in the superficial (P = .003) and deep plexuses (P = .029). Only deep parafoveal CPD values demonstrated correlation with VA (P = .043) CONCLUSIONS: Eyes with MI determined by masked qualitative OCTA grading demonstrated significantly reduced CPD values compared to normal eyes. Categorical assessment of MI severity correlated with VA. [Ophthalmic Surg Lasers Imaging Retina. 2020;51:S30-S36.]
Beschreibung:	Date Completed 14.04.2021 Date Revised 10.09.2024 published: Print Citation Status MEDLINE
ISSN:	2325-8179
DOI:	10.3928/23258160-20200401-04