Differential Interactions of Piscidins with Phospholipids and Lipopolysaccharides at Membrane Interfaces

Piscidins 1 and 3 (P1 and P3) are potent antimicrobial peptides isolated from striped bass. Their mechanism of action involves formation of amphipathic α-helices on contact with phospholipids and destabilization of the microbial cytoplasmic membrane. The peptides are active against both Gram-positiv...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 36(2020), 18 vom: 12. Mai, Seite 5065-5077
1. Verfasser: Cetuk, Hannah (VerfasserIn)
Weitere Verfasser: Maramba, Joseph, Britt, Madolyn, Scott, Alison J, Ernst, Robert K, Mihailescu, Mihaela, Cotten, Myriam L, Sukharev, Sergei
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2020
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S. Anti-Bacterial Agents Lipopolysaccharides Phospholipids