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231225s2020 xx |||||o 00| ||eng c |
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|a 10.1109/TUFFC.2020.2983732
|2 doi
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|a pubmed25n1028.xml
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|e rakwb
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|a eng
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| 100 |
1 |
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|a Li, Yang
|e verfasserin
|4 aut
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| 245 |
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|a 3-D X-Ray-Induced Acoustic Computed Tomography With a Spherical Array
|b A Simulation Study on Bone Imaging
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|c 2020
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|a Text
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|a ƒaComputermedien
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|a Date Completed 21.06.2021
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|a Date Revised 21.06.2021
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a X-ray-induced acoustic computed tomography (XACT) is a promising imaging modality combining high X-ray absorption contrast with the 3-D propagation advantages provided by high-resolution ultrasound waves. The purpose of this study was to optimize the configuration of a 3-D XACT imaging system for bone imaging. A 280 ultrasonic sensors with peak frequency of 10 MHz was designed to distribute on a spherical surface to optimize the 3-D volumetric imaging capability. We performed both theoretical calculations and simulations of this optimized XACT imaging configuration on a mouse-sized digital phantom containing various X-ray absorption coefficients. Iteration algorithm based on total variation has been used for 3-D XACT image reconstruction. The spatial resolution of imaging was estimated to about [Formula: see text] along both axial and lateral directions. We simulate XACT imaging of bone microstructures using digital phantoms generated from micro-CT images of real biological samples, showing that XACT imaging can provide high-resolution imaging of the mouse paw. Results of this study will greatly enhance the potential of XACT imaging in the evaluation of bone diseases for future clinical use
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|a Journal Article
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|a Research Support, N.I.H., Extramural
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|a Research Support, Non-U.S. Gov't
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|a Samant, Pratik
|e verfasserin
|4 aut
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|a Wang, Siqi
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Behrooz, A
|e verfasserin
|4 aut
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|a Li, Dengwang
|e verfasserin
|4 aut
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| 700 |
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|a Xiang, Liangzhong
|e verfasserin
|4 aut
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|i Enthalten in
|t IEEE transactions on ultrasonics, ferroelectrics, and frequency control
|d 1986
|g 67(2020), 8 vom: 14. Aug., Seite 1613-1619
|w (DE-627)NLM098181017
|x 1525-8955
|7 nnas
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| 773 |
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|g volume:67
|g year:2020
|g number:8
|g day:14
|g month:08
|g pages:1613-1619
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|u http://dx.doi.org/10.1109/TUFFC.2020.2983732
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