Phytochemical- and Cyclodextrin-Based Pickering Emulsions : Natural Potentiators of Antibacterial, Antifungal, and Antibiofilm Activity

We present self-assembled Pickering emulsions containing biocidal phytochemical oils (carvacrol and terpinen-4-ol) and β-cyclodextrin able to potentiate the antimicrobial and antibiofilm activity of miconazoctylium bromide. The carvacrol-containing emulsion is 2-fold more sensitive against C. albica...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 36(2020), 16 vom: 28. Apr., Seite 4317-4323
1. Verfasser: Leclercq, Loïc (VerfasserIn)
Weitere Verfasser: Tessier, Jérémie, Douyère, Grégory, Nardello-Rataj, Véronique, Schmitzer, Andreea R
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2020
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Anti-Bacterial Agents Antifungal Agents Cyclodextrins Cymenes Emulsions Terpenes terpinenol-4 562-74-3 mehr... carvacrol 9B1J4V995Q
LEADER 01000naa a22002652 4500
001 NLM308567463
003 DE-627
005 20231225132014.0
007 cr uuu---uuuuu
008 231225s2020 xx |||||o 00| ||eng c
024 7 |a 10.1021/acs.langmuir.0c00314  |2 doi 
028 5 2 |a pubmed24n1028.xml 
035 |a (DE-627)NLM308567463 
035 |a (NLM)32271592 
040 |a DE-627  |b ger  |c DE-627  |e rakwb 
041 |a eng 
100 1 |a Leclercq, Loïc  |e verfasserin  |4 aut 
245 1 0 |a Phytochemical- and Cyclodextrin-Based Pickering Emulsions  |b Natural Potentiators of Antibacterial, Antifungal, and Antibiofilm Activity 
264 1 |c 2020 
336 |a Text  |b txt  |2 rdacontent 
337 |a ƒaComputermedien  |b c  |2 rdamedia 
338 |a ƒa Online-Ressource  |b cr  |2 rdacarrier 
500 |a Date Completed 09.11.2020 
500 |a Date Revised 09.11.2020 
500 |a published: Print-Electronic 
500 |a Citation Status MEDLINE 
520 |a We present self-assembled Pickering emulsions containing biocidal phytochemical oils (carvacrol and terpinen-4-ol) and β-cyclodextrin able to potentiate the antimicrobial and antibiofilm activity of miconazoctylium bromide. The carvacrol-containing emulsion is 2-fold more sensitive against C. albicans and S. aureus and highly active against E. coli, compared to the commercial cream containing miconazole nitrate. Moreover, this emulsion shows a synergistic effect against fungi, additive responses against bacteria, and remarkable staphylococcal biofilm eradication. These results are associated with membrane permeabilization, enzymes inhibition, and the accumulation of reactive oxygen species in microorganisms 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
650 7 |a Anti-Bacterial Agents  |2 NLM 
650 7 |a Antifungal Agents  |2 NLM 
650 7 |a Cyclodextrins  |2 NLM 
650 7 |a Cymenes  |2 NLM 
650 7 |a Emulsions  |2 NLM 
650 7 |a Terpenes  |2 NLM 
650 7 |a terpinenol-4  |2 NLM 
650 7 |a 562-74-3  |2 NLM 
650 7 |a carvacrol  |2 NLM 
650 7 |a 9B1J4V995Q  |2 NLM 
700 1 |a Tessier, Jérémie  |e verfasserin  |4 aut 
700 1 |a Douyère, Grégory  |e verfasserin  |4 aut 
700 1 |a Nardello-Rataj, Véronique  |e verfasserin  |4 aut 
700 1 |a Schmitzer, Andreea R  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Langmuir : the ACS journal of surfaces and colloids  |d 1992  |g 36(2020), 16 vom: 28. Apr., Seite 4317-4323  |w (DE-627)NLM098181009  |x 1520-5827  |7 nnns 
773 1 8 |g volume:36  |g year:2020  |g number:16  |g day:28  |g month:04  |g pages:4317-4323 
856 4 0 |u http://dx.doi.org/10.1021/acs.langmuir.0c00314  |3 Volltext 
912 |a GBV_USEFLAG_A 
912 |a SYSFLAG_A 
912 |a GBV_NLM 
912 |a GBV_ILN_22 
912 |a GBV_ILN_350 
912 |a GBV_ILN_721 
951 |a AR 
952 |d 36  |j 2020  |e 16  |b 28  |c 04  |h 4317-4323