Self-Assembly of Integrin Ligands on the Apical Membrane Inhibits the Migration of Glioma Cells

Malignant brain cancer remains challenging in treatment due to the highly invasive quality of gliomas. Inspired by the upregulated expression of integrin β1 subunits in tumors, we designed and synthesized an integrin-targeting self-assembling ligand based on a laminin-derived peptide that selectivel...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 36(2020), 14 vom: 14. Apr., Seite 3750-3757
1. Verfasser: Mang, Dingze (VerfasserIn)
Weitere Verfasser: Roy, Sona Rani, Hoh, Hong Huat, Wu, Xia, Zhang, Jiahao, Jin, Chengzhi, Zhang, Ye
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2020
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Integrin beta1 Integrins Ligands