|
|
|
|
| LEADER |
01000naa a22002652 4500 |
| 001 |
NLM306633868 |
| 003 |
DE-627 |
| 005 |
20231225123813.0 |
| 007 |
cr uuu---uuuuu |
| 008 |
231225s2020 xx |||||o 00| ||eng c |
| 024 |
7 |
|
|a 10.1021/acs.langmuir.9b02942
|2 doi
|
| 028 |
5 |
2 |
|a pubmed24n1022.xml
|
| 035 |
|
|
|a (DE-627)NLM306633868
|
| 035 |
|
|
|a (NLM)32069411
|
| 040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
| 041 |
|
|
|a eng
|
| 100 |
1 |
|
|a Urban, Patrick
|e verfasserin
|4 aut
|
| 245 |
1 |
2 |
|a A Lipid Photoswitch Controls Fluidity in Supported Bilayer Membranes
|
| 264 |
|
1 |
|c 2020
|
| 336 |
|
|
|a Text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a ƒaComputermedien
|b c
|2 rdamedia
|
| 338 |
|
|
|a ƒa Online-Ressource
|b cr
|2 rdacarrier
|
| 500 |
|
|
|a Date Completed 29.07.2020
|
| 500 |
|
|
|a Date Revised 29.07.2020
|
| 500 |
|
|
|a published: Print-Electronic
|
| 500 |
|
|
|a Citation Status PubMed-not-MEDLINE
|
| 520 |
|
|
|a Supported lipid bilayer (SLB) membranes are key elements to mimic membrane interfaces on a planar surface. Here, we demonstrate that azobenzene photolipids (azo-PC) form fluid, homogeneous SLBs. Diffusion properties of azo-PC within SLBs were probed by fluorescence microscopy and fluorescence recovery after photobleaching. At ambient conditions, we find that the trans-to-cis isomerization causes an increase of the diffusion constant by a factor of two. Simultaneous excitation with two wavelengths and variable intensities furthermore allows to adjust the diffusion constant D continuously. X-ray reflectometry and small-angle scattering measurements reveal that membrane photoisomerization results in a bilayer thickness reduction of ∼0.4 nm (or 10%). While thermally induced back-switching is not observed, we find that the trans bilayer fluidity is increasing with higher temperatures. This change in diffusion constant is accompanied by a red-shift in the absorption spectra. Based on these results, we suggest that the reduced diffusivity of trans-azo-PC is controlled by intermolecular interactions that also give rise to H-aggregate formation in bilayer membranes
|
| 650 |
|
4 |
|a Journal Article
|
| 650 |
|
4 |
|a Research Support, Non-U.S. Gov't
|
| 650 |
|
4 |
|a Research Support, U.S. Gov't, Non-P.H.S.
|
| 700 |
1 |
|
|a Pritzl, Stefanie D
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Ober, Martina F
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Dirscherl, Christina F
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Pernpeintner, Carla
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Konrad, David B
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Frank, James A
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Trauner, Dirk
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Nickel, Bert
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Lohmueller, Theobald
|e verfasserin
|4 aut
|
| 773 |
0 |
8 |
|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1992
|g 36(2020), 10 vom: 17. März, Seite 2629-2634
|w (DE-627)NLM098181009
|x 1520-5827
|7 nnns
|
| 773 |
1 |
8 |
|g volume:36
|g year:2020
|g number:10
|g day:17
|g month:03
|g pages:2629-2634
|
| 856 |
4 |
0 |
|u http://dx.doi.org/10.1021/acs.langmuir.9b02942
|3 Volltext
|
| 912 |
|
|
|a GBV_USEFLAG_A
|
| 912 |
|
|
|a SYSFLAG_A
|
| 912 |
|
|
|a GBV_NLM
|
| 912 |
|
|
|a GBV_ILN_22
|
| 912 |
|
|
|a GBV_ILN_350
|
| 912 |
|
|
|a GBV_ILN_721
|
| 951 |
|
|
|a AR
|
| 952 |
|
|
|d 36
|j 2020
|e 10
|b 17
|c 03
|h 2629-2634
|