Conventional and innovative methods to assess oxidative stress biomarkers in the clinical cardiovascular setting

Oxidative stress has a pivotal and widely described role in the onset and progression of atherosclerotic plaque and cardiovascular disease. Many oxidative stress-related biomarkers can be measured in biological samples; however, there are still many aspects that limit the adoption of oxidative stres...

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Veröffentlicht in:BioTechniques. - 1993. - 68(2020), 4 vom: 11. Apr., Seite 223-231
1. Verfasser: Gaggini, Melania (VerfasserIn)
Weitere Verfasser: Sabatino, Laura, Vassalle, Cristina
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2020
Zugriff auf das übergeordnete Werk:BioTechniques
Schlagworte:Journal Article Review antioxidants ceramides lipid peroxidation lipidomics oxidative stress total antioxidant capacity Antioxidants Biomarkers Ceramides
Beschreibung
Zusammenfassung:Oxidative stress has a pivotal and widely described role in the onset and progression of atherosclerotic plaque and cardiovascular disease. Many oxidative stress-related biomarkers can be measured in biological samples; however, there are still many aspects that limit the adoption of oxidative stress assessment in clinical laboratory practice. Here, we report an overview of the different sources and main common oxidative stress biomarkers relevant for cardiovascular physiopathology, describing in detail a recently proposed lipidomic assay for ceramide assessment, as a promising future development in oxidative stress evaluation among the many available redox-related tests
Beschreibung:Date Completed 14.09.2021
Date Revised 14.09.2021
published: Print-Electronic
Citation Status MEDLINE
ISSN:1940-9818
DOI:10.2144/btn-2019-0138