Hot melt extruded-based nano zinc as an alternative to the pharmacological dose of ZnO in weanling piglets

OBJECTIVE: This study was conducted to investigate the effects of hot-melt extruded ZnO nano-particles (HME-ZnO) as an alternative for P-ZnO on growth performance, nutrient digestibility, Zn bioavailability, intestinal microbiota, and intestinal morphology of weanling pigs

Bibliographische Detailangaben
Veröffentlicht in:Asian-Australasian journal of animal sciences. - 1998. - 33(2020), 6 vom: 12. Juni, Seite 992-1001
1. Verfasser: Oh, Seung Min (VerfasserIn)
Weitere Verfasser: Kim, Min Ju, Hosseindoust, Abdolreza, Kim, Kwang Yeol, Choi, Yo Han, Ham, Hyung Bin, Hwang, Sung Jun, Lee, Jun Hyung, Cho, Hyun Jong, Kang, Wei Soo, Chae, Byung Jo
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2020
Zugriff auf das übergeordnete Werk:Asian-Australasian journal of animal sciences
Schlagworte:Journal Article Bioavailability Microbiota Nano Zinc Villus Height Weaned Pigs
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520 |a OBJECTIVE: This study was conducted to investigate the effects of hot-melt extruded ZnO nano-particles (HME-ZnO) as an alternative for P-ZnO on growth performance, nutrient digestibility, Zn bioavailability, intestinal microbiota, and intestinal morphology of weanling pigs 
520 |a METHODS: A total of 450 piglets (Landrace×Yorkshire×Duroc) were randomly allotted to five treatments based on initial body weight and sex. The experimental diets were fed in a meal form as phase 1 from d 0 to 14 and phase 2 from d 15 to 28. Treatments were the control diet without ZnO supplementation, the diet containing 2,500 ppm Zn as ZnO, and three diets containing 500, 1,000, or 2,500 ppm Zn as HME-ZnO 
520 |a RESULTS: The overall result showed a higher (p<0.01) average daily gain in weanling pigs fed ZnO-supplemented diets in comparison to the control diet. There was a decrease (p<0.01) in fecal score in the ZnO-supplemented diets. Dietary supplementation of ZnO improved (p<0.05) crude protein digestibility. The weanling pigs fed the P-ZnO diet had a lower (p<0.01) Zn digestibility in the feces than HME-ZnO supplemented treatments. Weanling pigs fed diets supplemented with ZnO had greater (p<0.05) Lactobacillus spp. populations and lower Clostridium spp. (p<0.05) and Coliforms (p<0.01) populations in the ileum. Weanling pigs fed diets supplemented with increasing concentrations of HME-ZnO linearly decreased Clostridium spp. (p<0.05) and Coliforms (p<0.01) in the ileum. Lower (p<0.05) Clostridium spp. and Coliforms counts in the colon were observed in pigs fed with ZnO-supplemented diets. Weanling pigs fed diets supplemented with ZnO showed a greater (p<0.01) villus height in the duodenum 
520 |a CONCLUSION: Dietary supplementation of HME-ZnO and P-ZnO showed a potential to improve the digestibility of protein, intestinal Coliform and Clostridium, villus height in duodenum and ileum. Moreover, HME-ZnO showed a higher Zn digestibility compared with P-ZnO 
650 4 |a Journal Article 
650 4 |a Bioavailability 
650 4 |a Microbiota 
650 4 |a Nano Zinc 
650 4 |a Villus Height 
650 4 |a Weaned Pigs 
700 1 |a Kim, Min Ju  |e verfasserin  |4 aut 
700 1 |a Hosseindoust, Abdolreza  |e verfasserin  |4 aut 
700 1 |a Kim, Kwang Yeol  |e verfasserin  |4 aut 
700 1 |a Choi, Yo Han  |e verfasserin  |4 aut 
700 1 |a Ham, Hyung Bin  |e verfasserin  |4 aut 
700 1 |a Hwang, Sung Jun  |e verfasserin  |4 aut 
700 1 |a Lee, Jun Hyung  |e verfasserin  |4 aut 
700 1 |a Cho, Hyun Jong  |e verfasserin  |4 aut 
700 1 |a Kang, Wei Soo  |e verfasserin  |4 aut 
700 1 |a Chae, Byung Jo  |e verfasserin  |4 aut 
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773 1 8 |g volume:33  |g year:2020  |g number:6  |g day:12  |g month:06  |g pages:992-1001 
856 4 0 |u http://dx.doi.org/10.5713/ajas.19.0140  |3 Volltext 
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