Zwitterionic Polymer Micelles with Dual Conjugation of Doxorubicin and Curcumin : Synergistically Enhanced Efficacy against Multidrug-Resistant Tumor Cells

This paper reports a novel redox-sensitive micellar system for the co-delivery of doxorubicin (Dox) and a chemosensitizer (curcumin, Cur) to overcome the multidrug resistance (MDR) in cancer cells. Dox and Cur were co-conjugated onto a zwitterionic polymer, poly(carboxybetaine) (pCB), to form Cur-pC...

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Veröffentlicht in:	Langmuir : the ACS journal of surfaces and colloids. - 1992. - 36(2020), 9 vom: 10. März, Seite 2383-2395
1. Verfasser:	Zhao, Guangfu (VerfasserIn)
Weitere Verfasser:	Sun, Yan, Dong, Xiaoyan
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2020
Zugriff auf das übergeordnete Werk:	Langmuir : the ACS journal of surfaces and colloids
Schlagworte:	Journal Article Research Support, Non-U.S. Gov't Antineoplastic Agents Drug Carriers Methacrylates Micelles Polymethacrylic Acids polycarboxybetaine methacrylate sulfobetaine methacrylate polymer Betaine mehr... 3SCV180C9W Doxorubicin 80168379AG Curcumin IT942ZTH98