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231225s2020 xx |||||o 00| ||eng c |
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|a 10.1021/acs.langmuir.9b03489
|2 doi
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|e rakwb
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|a eng
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| 100 |
1 |
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|a Jing, Jie
|e verfasserin
|4 aut
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| 245 |
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|a Two-Dimensional Immiscible Domain of Cholesterol in the Lipid Bilayer Membrane Promotes Early Stage Calcification by Inducing Oriented Nucleation of Hydroxyapatite
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|c 2020
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|a Text
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|a ƒaComputermedien
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|a Date Completed 23.07.2020
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|a Date Revised 23.07.2020
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|a published: Print-Electronic
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|a Citation Status PubMed-not-MEDLINE
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|a Biomineralization is characterized by the fact that the crystallization of inorganic minerals is guided by an in vivo biological interface. However, the interfaces that direct calcification are widely debated up to date. In this paper, it was found that the two-dimensional (2D) immiscible domain of cholesterol in the lipid bilayer can induce the deposition of calcium phosphate by rapidly promoting the nucleation of the hydroxyapatite (001) plane. This promotion effect is related to the high lattice matching degree between the 2D cholesterol immiscible domain and the (001) plane of hydroxyapatite (HAP), which leads to the heteroepitaxy of HAP. The lipid bilayer derived from cells or vesicles is the largest biological interface in the body, thus revealing whether the lipid bilayer can induce the deposition of calcium phosphate will facilitate the understanding of the important role of cells or vesicles in calcification
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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| 700 |
1 |
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|a Chen, Xuanyu
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Meng, Zhiping
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Su, Wenqiang
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Liu, Yonghai
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Zhang, Yue
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Zhu, Huaxu
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Yao, Weiwei
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Fu, Tingming
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1992
|g 36(2020), 8 vom: 03. März, Seite 2136-2142
|w (DE-627)NLM098181009
|x 1520-5827
|7 nnns
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| 773 |
1 |
8 |
|g volume:36
|g year:2020
|g number:8
|g day:03
|g month:03
|g pages:2136-2142
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| 856 |
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|u http://dx.doi.org/10.1021/acs.langmuir.9b03489
|3 Volltext
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