Acidic Environment Significantly Alters Aggregation Pathway of Human Islet Amyloid Polypeptide at Negative Lipid Membrane

The misfolding and aggregation of human islet amyloid polypeptide (hIAPP) at cell membrane has a close relationship with the development of type 2 diabetes (T2DM). This aggregation process is susceptible to various physiologically related factors, and systematic studies on condition-mediated hIAPP a...

Description complète

Détails bibliographiques
Publié dans:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 36(2020), 6 vom: 18. Feb., Seite 1530-1537
Auteur principal: Zhang, Jiahui (Auteur)
Autres auteurs: Tan, Junjun, Pei, Ruoqi, Ye, Shuji
Format: Article en ligne
Langue:English
Publié: 2020
Accès à la collection:Langmuir : the ACS journal of surfaces and colloids
Sujets:Journal Article Research Support, Non-U.S. Gov't Amyloid Islet Amyloid Polypeptide Lipids