Influence of metronidazole on activated sludge activity

Metronidazole is potentially carcinogenic to humans and it has been detected in wastewaters. The Wastewater Treatment Plants using biological processes have been highly impacted by the emergent compounds of recalcitrant type, and the knowledge about that issue is quite relevant. Therefore, this pape...

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Veröffentlicht in:Environmental technology. - 1993. - 42(2021), 18 vom: 02. Juli, Seite 2815-2822
1. Verfasser: Velasco-Garduño, Oscar (VerfasserIn)
Weitere Verfasser: González-Blanco, Gehovana, Fajardo-Ortiz, María Del Carmen, Beristain-Cardoso, Ricardo
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2021
Zugriff auf das übergeordnete Werk:Environmental technology
Schlagworte:Journal Article Metronidazole heterotrophic-activity kinetics metabolism nitrification Ammonium Compounds Nitrites Sewage Waste Water 140QMO216E
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520 |a Metronidazole is potentially carcinogenic to humans and it has been detected in wastewaters. The Wastewater Treatment Plants using biological processes have been highly impacted by the emergent compounds of recalcitrant type, and the knowledge about that issue is quite relevant. Therefore, this paper was focused on how metronidazole influences the kinetics and metabolic behaviour of nitrification and heterotrophic activity on activated sludge in batch cultures. Eight concentrations of metronidazole in the range of 5-100 mg/L were evaluated, in the presence of 2109 ± 129 mg VSS/L. The increment of initial metronidazole concentration caused a decline on COD and ammonium removal efficiencies, nitrate production yields, as well as in the substrate-specific consumption rates. Metronidazole (MDZ) had a greater impact on heterotrophic activity than nitrifying activity; also, it had a greater inhibitory effect on nitrite oxidation than ammonium oxidation. The activated sludge was not able to biotransform metronidazole; however, the azole compound significantly affected the physiology of it. The inhibition of ammonium oxidation was non-competitive (qmax = 120 mg NH4+-N consumed/gVSS-d, and Ki = 41.5 mg MDZ/L) and the initial metronidazole concentration that inhibited 50% of nitrifying activity (IC50) was 43 mg MDZ/L 
650 4 |a Journal Article 
650 4 |a Metronidazole 
650 4 |a heterotrophic-activity 
650 4 |a kinetics 
650 4 |a metabolism 
650 4 |a nitrification 
650 7 |a Ammonium Compounds  |2 NLM 
650 7 |a Nitrites  |2 NLM 
650 7 |a Sewage  |2 NLM 
650 7 |a Waste Water  |2 NLM 
650 7 |a Metronidazole  |2 NLM 
650 7 |a 140QMO216E  |2 NLM 
700 1 |a González-Blanco, Gehovana  |e verfasserin  |4 aut 
700 1 |a Fajardo-Ortiz, María Del Carmen  |e verfasserin  |4 aut 
700 1 |a Beristain-Cardoso, Ricardo  |e verfasserin  |4 aut 
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773 1 8 |g volume:42  |g year:2021  |g number:18  |g day:02  |g month:07  |g pages:2815-2822 
856 4 0 |u http://dx.doi.org/10.1080/09593330.2020.1714746  |3 Volltext 
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