Nanoscopic X-ray imaging and quantification of the iron cellular architecture within single fibroblasts of Friedreich's ataxia patients

Friedreich's ataxia (FRDA) is a neurodegenerative disease characterized by an increase in intracytoplasmic iron concentration. Here the nanoscale iron distribution within single fibroblasts from FRDA patients was investigated using synchrotron-radiation-based nanoscopic X-ray fluorescence and X...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Journal of synchrotron radiation. - 1994. - 27(2020), Pt 1 vom: 01. Jan., Seite 185-198
1. Verfasser: De Samber, Björn (VerfasserIn)
Weitere Verfasser: Vanden Berghe, Tom, Meul, Eline, Bauters, Stephen, Seyrich, Martin, Smet, Joél, De Paepe, Boel, da Silva, Julio Cesar, Bohic, Sylvain, Cloetens, Peter, Van Coster, Rudy, Vandenabeele, Peter, Vincze, Laszlo
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2020
Zugriff auf das übergeordnete Werk:Journal of synchrotron radiation
Schlagworte:Journal Article Friedreich's ataxia imaging iron nano-XRF quantification Carbon 7440-44-0 Iron E1UOL152H7