Detecting G protein-coupled receptor complexes in postmortem human brain with proximity ligation assay and a Bayesian classifier

Despite the controversy regarding the existence and physiological relevance of class A G protein-coupled receptor dimerization, there is substantial evidence for functional interactions between the dopamine D2 receptor (D2R) and the adenosine A2A receptor (A2AR). A2AR-D2R complexes have been detecte...

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Veröffentlicht in:BioTechniques. - 1991. - 68(2020), 3 vom: 01. März, Seite 122-129
1. Verfasser: Zhu, Ying (VerfasserIn)
Weitere Verfasser: Mészáros, József, Walle, Roman, Fan, Rongxi, Sun, Ziyi, Dwork, Andrew J, Trifilieff, Pierre, Javitch, Jonathan A
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2020
Zugriff auf das übergeordnete Werk:BioTechniques
Schlagworte:Journal Article Research Support, N.I.H., Extramural G protein-coupled receptor adenosine adenosine A2A receptor dopamine dopamine receptor type 2 machine learning naive Bayesian classifier proximity ligation assay mehr... Receptor, Adenosine A2A Receptors, Dopamine D2 Receptors, G-Protein-Coupled