Affimers as anti-idiotypic affinity reagents for pharmacokinetic analysis of biotherapeutics
Therapeutic antibodies are the fastest growing class of drugs in the treatment of cancer, and autoimmune and inflammatory diseases that require the concomitant development of assays to monitor therapeutic antibody levels. Here, we demonstrate that the use of Affimer nonantibody binding proteins prov...
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Bibliographische Detailangaben
| Veröffentlicht in: | BioTechniques. - 1988. - 67(2019), 6 vom: 01. Dez., Seite 261-269
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| 1. Verfasser: |
Adamson, Hope
(VerfasserIn) |
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| Weitere Verfasser: |
Nicholl, Amanda,
Tiede, Christian,
Tang, Anna A,
Davidson, Alex,
Curd, Helen,
Wignall, Alex,
Ford, Robert,
Nuttall, James,
McPherson, Michael J,
Johnson, Matt,
Tomlinson, Darren C |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2019
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| Zugriff auf das übergeordnete Werk: | BioTechniques
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| Schlagworte: | Journal Article
Affimer reagents
anti-idiotypic
biotherapeutics
diagnostics
pharmacokinetics
Antibodies, Monoclonal |
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