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231225s2020 xx |||||o 00| ||eng c |
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|a 10.1002/adma.201904351
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|a eng
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|a Zhang, Zhen
|e verfasserin
|4 aut
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|a Engineering Smart Nanofluidic Systems for Artificial Ion Channels and Ion Pumps
|b From Single-Pore to Multichannel Membranes
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|c 2020
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|a Text
|b txt
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|a ƒaComputermedien
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|a Date Completed 21.10.2020
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|a Date Revised 21.10.2020
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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|a Biological ion channels and ion pumps with intricate ion transport functions widely exist in living organisms and play irreplaceable roles in almost all physiological functions. Nanofluidics provides exciting opportunities to mimic these working processes, which not only helps understand ion transport in biological systems but also paves the way for the applications of artificial devices in many valuable areas. Recent progress in the engineering of smart nanofluidic systems for artificial ion channels and ion pumps is summarized. The artificial systems range from chemically and structurally diverse lipid-membrane-based nanopores to robust and scalable solid-state nanopores. A generic strategy of gate location design is proposed. The single-pore-based platform concept can be rationally extended into multichannel membrane systems and shows unprecedented potential in many application areas, such as single-molecule analysis, smart mass delivery, and energy conversion. Finally, some present underpinning issues that need to be addressed are discussed
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|a Journal Article
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|a Review
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|a bioinspiration
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|a ion channels
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|a ion pumps
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|a nanofluidics
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|a smart materials
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|a Ion Channels
|2 NLM
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|a Ion Pumps
|2 NLM
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|a Lipids
|2 NLM
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|a Huang, Xiaodong
|e verfasserin
|4 aut
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|a Qian, Yongchao
|e verfasserin
|4 aut
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|a Chen, Weipeng
|e verfasserin
|4 aut
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|a Wen, Liping
|e verfasserin
|4 aut
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|a Jiang, Lei
|e verfasserin
|4 aut
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|i Enthalten in
|t Advanced materials (Deerfield Beach, Fla.)
|d 1998
|g 32(2020), 4 vom: 09. Jan., Seite e1904351
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|x 1521-4095
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|g volume:32
|g year:2020
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|g day:09
|g month:01
|g pages:e1904351
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