The Binding of Drug Molecules to Serum Albumin : The Effect of Drug Hydrophobicity on Binding Strength and Protein Desolvation

In this work, dual polarization interferometry (DPI) and quartz crystal microgravimetry with dissipation monitoring (QCM-D) were used to examine the binding characteristics and structure-activity relationships of 12 common drugs on a model bovine serum albumin (BSA) film. By taking advantage of the...

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Veröffentlicht in:	Langmuir : the ACS journal of surfaces and colloids. - 1999. - 35(2019), 52 vom: 31. Dez., Seite 17054-17060
1. Verfasser:	Al-Husseini, Jacob K (VerfasserIn)
Weitere Verfasser:	Stanton, Noah J, Selassie, Cynthia R D, Johal, Malkiat S
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2019
Zugriff auf das übergeordnete Werk:	Langmuir : the ACS journal of surfaces and colloids
Schlagworte:	Journal Article Research Support, Non-U.S. Gov't Pharmaceutical Preparations Solvents Serum Albumin, Bovine 27432CM55Q