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231225s2021 xx |||||o 00| ||eng c |
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|a 10.1002/mrc.4968
|2 doi
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|a pubmed24n1010.xml
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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|a de Melo Sousa, Cleyton Marcos
|e verfasserin
|4 aut
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|a Effect of the solvent on the conformation of monocrotaline as determined by isotropic and anisotropic NMR parameters
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|c 2021
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
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|2 rdacarrier
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|a Date Completed 24.05.2021
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|a Date Revised 24.05.2021
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|a published: Print-Electronic
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|a Citation Status PubMed-not-MEDLINE
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|a © 2019 John Wiley & Sons, Ltd.
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|a The conformation in solution of monocrotaline, a pyrrolizidine alkaloid presenting an eleven-membered macrocyclic diester ring, has been investigated using a combination of isotropic and anisotropic nuclear magnetic resonance parameters measured in four solvents of different polarity (D2 O, DMSO-d6 , CDCl3 , and C6 D6 ). Anisotropic nuclear magnetic resonance parameters were measured in different alignment media, based on their compatibility with the solvent of interest: cromoglycate liquid crystal solution was used for D2 O, whereas a poly (methyl methacrylate) polymer gel was chosen for CDCl3 and C6 D6 , and a poly (hydroxyethyl methacrylate) gel for DMSO-d6 . Whereas the pyrrolizidine ring shows an E6 exo-puckered conformation in all of the solvents, the macrocyclic eleven-membered ring adopts different populations of syn-parallel and anti-parallel relative orientation of the carbonyl groups according to the polarity of the solvent
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|a Journal Article
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|a Research Support, U.S. Gov't, Non-P.H.S.
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|a Research Support, Non-U.S. Gov't
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|a 13C
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|a 1H
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|a NMR
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|a RDC
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|a conformation
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|a monocrotaline
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|a Giordani, Raquel Brandt
|e verfasserin
|4 aut
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|a de Almeida, Wamberto Alristenio Moreira
|e verfasserin
|4 aut
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|a Griesinger, Christian
|e verfasserin
|4 aut
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|a Gil, Roberto R
|e verfasserin
|4 aut
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|a Navarro-Vázquez, Armando
|e verfasserin
|4 aut
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|a Hallwass, Fernando
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Magnetic resonance in chemistry : MRC
|d 1985
|g 59(2021), 5 vom: 02. Mai, Seite 561-568
|w (DE-627)NLM098179667
|x 1097-458X
|7 nnns
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|g volume:59
|g year:2021
|g number:5
|g day:02
|g month:05
|g pages:561-568
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|u http://dx.doi.org/10.1002/mrc.4968
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