Quantified Membrane Permeabilization Indicates the Lipid Selectivity of Membrane-Active Antimicrobials
Most antimicrobial peptides (AMPs) and their synthetic mimics (SMAMPs) are thought to act by permeabilizing cell membranes. For antimicrobial therapy, selectivity for pathogens over mammalian cells is a key requirement. Understanding membrane selectivity is thus essential for designing AMPs and SMAM...
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Bibliographische Detailangaben
| Veröffentlicht in: | Langmuir : the ACS journal of surfaces and colloids. - 1992. - 35(2019), 49 vom: 10. Dez., Seite 16366-16376
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| 1. Verfasser: |
Stulz, Anja
(VerfasserIn) |
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| Weitere Verfasser: |
Vogt, Annika,
Saar, Julia Selina,
Akil, Larissa,
Lienkamp, Karen,
Hoernke, Maria |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2019
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| Zugriff auf das übergeordnete Werk: | Langmuir : the ACS journal of surfaces and colloids
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| Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
Anti-Infective Agents |
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