Mixed Carboxyl and Hydrophobic Dendrimer Surface Inhibits Amyloid-β Fibrillation : New Insight from the Generation Number Effect

Fibrillation of amyloid-β peptide (Aβ) is closely associated with the progression of Alzheimer's disease (AD), and so inhibition of Aβ fibrillation has been considered as one of the promising strategies for AD prevention and treatment. Our group has proposed the hydrophobic binding-electrostati...

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Publié dans:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 35(2019), 45 vom: 12. Nov., Seite 14681-14687
Auteur principal: Wang, Ziyuan (Auteur)
Autres auteurs: Dong, Xiaoyan, Sun, Yan
Format: Article en ligne
Langue:English
Publié: 2019
Accès à la collection:Langmuir : the ACS journal of surfaces and colloids
Sujets:Journal Article Research Support, Non-U.S. Gov't Amyloid beta-Peptides Dendrimers Poly(amidoamine) Polyamines