|
|
|
|
| LEADER |
01000naa a22002652 4500 |
| 001 |
NLM301684774 |
| 003 |
DE-627 |
| 005 |
20231225105135.0 |
| 007 |
cr uuu---uuuuu |
| 008 |
231225s2020 xx |||||o 00| ||eng c |
| 024 |
7 |
|
|a 10.1111/nph.16220
|2 doi
|
| 028 |
5 |
2 |
|a pubmed24n1005.xml
|
| 035 |
|
|
|a (DE-627)NLM301684774
|
| 035 |
|
|
|a (NLM)31560799
|
| 040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
| 041 |
|
|
|a eng
|
| 100 |
1 |
|
|a Lu, Wenjie
|e verfasserin
|4 aut
|
| 245 |
1 |
0 |
|a Linkage-linkage disequilibrium dissection of the epigenetic quantitative trait loci (epiQTLs) underlying growth and wood properties in Populus
|
| 264 |
|
1 |
|c 2020
|
| 336 |
|
|
|a Text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a ƒaComputermedien
|b c
|2 rdamedia
|
| 338 |
|
|
|a ƒa Online-Ressource
|b cr
|2 rdacarrier
|
| 500 |
|
|
|a Date Completed 16.12.2020
|
| 500 |
|
|
|a Date Revised 16.12.2020
|
| 500 |
|
|
|a published: Print-Electronic
|
| 500 |
|
|
|a Citation Status MEDLINE
|
| 520 |
|
|
|a © 2019 The Authors New Phytologist © 2019 New Phytologist Trust.
|
| 520 |
|
|
|a Increasing evidence indicates that DNA methylation is heritable and serves as an essential marker contributing to phenotypic variation. Linkage-linkage disequilibrium mapping was used to decipher the epigenetic architecture underlying nine growth and wood property traits in a linkage population (550 F1 progeny) and a natural population (435 unrelated individuals) of Populus using methylation-sensitive amplification polymorphism (MSAP)-based analysis. The interactions between genetic and epigenetic variants in the causative genes was further unveiled using expression quantitative trait methylation (eQTM) and nucleotide (eQTN) mapping strategies. A total of 163 epigenetic quantitative trait loci (epiQTLs; LOD ≥ 3.0), explaining 1.7-44.5% of phenotypic variations, were mapped to a high-resolution epigenetic map with 19 linkage groups, which was supported by the significant MSAP associations (P < 0.001) in the two populations. There were 23 causal genes involved in growth regulation and wood formation, whose markers were located in epiQTLs and associated with the same traits in both populations. Further eQTN and eQTM mapping showed that causal genetic and epigenetic variants within the 23 candidate genes may interact more in trans in gene expression and phenotype. The present study provides strategies for investigating epigenetic architecture and the interaction between genetic and epigenetic variants modulating complex traits in forest trees
|
| 650 |
|
4 |
|a Journal Article
|
| 650 |
|
4 |
|a Research Support, Non-U.S. Gov't
|
| 650 |
|
4 |
|a Populus
|
| 650 |
|
4 |
|a association genetics
|
| 650 |
|
4 |
|a eQTM
|
| 650 |
|
4 |
|a eQTN
|
| 650 |
|
4 |
|a epiQTL
|
| 650 |
|
4 |
|a epigenetic map
|
| 650 |
|
7 |
|a Genetic Markers
|2 NLM
|
| 700 |
1 |
|
|a Xiao, Liang
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Quan, Mingyang
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Wang, Qingshi
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a El-Kassaby, Yousry A
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Du, Qingzhang
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Zhang, Deqiang
|e verfasserin
|4 aut
|
| 773 |
0 |
8 |
|i Enthalten in
|t The New phytologist
|d 1979
|g 225(2020), 3 vom: 31. Feb., Seite 1218-1233
|w (DE-627)NLM09818248X
|x 1469-8137
|7 nnns
|
| 773 |
1 |
8 |
|g volume:225
|g year:2020
|g number:3
|g day:31
|g month:02
|g pages:1218-1233
|
| 856 |
4 |
0 |
|u http://dx.doi.org/10.1111/nph.16220
|3 Volltext
|
| 912 |
|
|
|a GBV_USEFLAG_A
|
| 912 |
|
|
|a SYSFLAG_A
|
| 912 |
|
|
|a GBV_NLM
|
| 912 |
|
|
|a GBV_ILN_350
|
| 951 |
|
|
|a AR
|
| 952 |
|
|
|d 225
|j 2020
|e 3
|b 31
|c 02
|h 1218-1233
|