Bioinspired Surface Functionalization of Titanium Alloy for Enhanced Lubrication and Bacterial Resistance

In clinics it is extremely important for implanted devices to achieve the property of enhanced lubrication and bacterial resistance; however, such a strategy has rarely been reported in previous literature. In the present study, a surface functionalization method, motivated by articular cartilage-in...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 35(2019), 40 vom: 08. Okt., Seite 13189-13195
1. Verfasser: Liu, Sizhe (VerfasserIn)
Weitere Verfasser: Zhang, Qian, Han, Ying, Sun, Yulong, Zhang, Yifei, Zhang, Hongyu
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2019
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Alloys Anti-Bacterial Agents Coated Materials, Biocompatible Lubricants Methacrylates poly(2-(dimethylamino)ethyl methacrylate-b-2-methacryloyloxyethyl phosphorylcholine) Phosphorylcholine 107-73-3 mehr... titanium alloy (TiAl6V4) 12743-70-3 Titanium D1JT611TNE
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520 |a In clinics it is extremely important for implanted devices to achieve the property of enhanced lubrication and bacterial resistance; however, such a strategy has rarely been reported in previous literature. In the present study, a surface functionalization method, motivated by articular cartilage-inspired superlubrication and mussel-inspired adhesion, was proposed to modify titanium alloy (Ti6Al4V) using the copolymer (DMA-MPC) synthesized via free radical copolymerization. The copolymer-coated Ti6Al4V (Ti6Al4VDMA-MPC) was evaluated by X-ray photoelectron spectroscopy, water contact angle, and Raman spectra to confirm that the DMA-MPC copolymer was successfully coated onto the Ti6Al4V substrate. In addition, the tribological test, with the polystyrene microsphere and Ti6Al4V or Ti6Al4V@DMA-MPC as the tribopair, indicated that the friction coefficient was greatly reduced for Ti6Al4V@DMA-MPC. Furthermore, the bacterial resistance test showed that bacterial attachment was significantly inhibited for Ti6Al4V@DMA-MPC for the three types of bacteria tested. The enhanced lubrication and bacterial resistance of Ti6Al4V@DMA-MPC was due to the tenacious hydration shell formed surrounding the zwitterionic charges in the phosphorylcholine group of the DMA-MPC copolymer. In summary, a bioinspired surface functionalization strategy is developed in this study, which can act as a universal and promising method to achieve enhanced lubrication and bacterial resistance for biomedical implants 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
650 7 |a Alloys  |2 NLM 
650 7 |a Anti-Bacterial Agents  |2 NLM 
650 7 |a Coated Materials, Biocompatible  |2 NLM 
650 7 |a Lubricants  |2 NLM 
650 7 |a Methacrylates  |2 NLM 
650 7 |a poly(2-(dimethylamino)ethyl methacrylate-b-2-methacryloyloxyethyl phosphorylcholine)  |2 NLM 
650 7 |a Phosphorylcholine  |2 NLM 
650 7 |a 107-73-3  |2 NLM 
650 7 |a titanium alloy (TiAl6V4)  |2 NLM 
650 7 |a 12743-70-3  |2 NLM 
650 7 |a Titanium  |2 NLM 
650 7 |a D1JT611TNE  |2 NLM 
700 1 |a Zhang, Qian  |e verfasserin  |4 aut 
700 1 |a Han, Ying  |e verfasserin  |4 aut 
700 1 |a Sun, Yulong  |e verfasserin  |4 aut 
700 1 |a Zhang, Yifei  |e verfasserin  |4 aut 
700 1 |a Zhang, Hongyu  |e verfasserin  |4 aut 
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