Interfacial Adsorption of a Monoclonal Antibody and Its Fab and Fc Fragments at the Oil/Water Interface
The physical stability of a monoclonal antibody (mAb) solution for injection in a prefilled syringe may in part depend on its behavior at the silicone oil/water interface. Here, the adsorption of a mAb (termed COE-3) and its fragment antigen-binding (Fab) and crystallizable (Fc) at the oil/water int...
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Bibliographische Detailangaben
| Veröffentlicht in: | Langmuir : the ACS journal of surfaces and colloids. - 1985. - 35(2019), 42 vom: 22. Okt., Seite 13543-13552
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| 1. Verfasser: |
Ruane, Sean
(VerfasserIn) |
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| Weitere Verfasser: |
Li, Zongyi,
Campana, Mario,
Hu, Xuzhi,
Gong, Haoning,
Webster, John R P,
Uddin, Faisal,
Kalonia, Cavan,
Bishop, Steven M,
van der Walle, Christopher F,
Lu, Jian R |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2019
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| Zugriff auf das übergeordnete Werk: | Langmuir : the ACS journal of surfaces and colloids
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| Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
Alkanes
Antibodies, Monoclonal
Immunoglobulin Fab Fragments
Immunoglobulin Fc Fragments
Oils
Water
059QF0KO0R
n-hexadecane
F8Z00SHP6Q |
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