Liposome-Mediated Chemotherapeutic Delivery Is Synergistically Enhanced by Ternary Lipid Compositions and Cationic Lipids

Most small molecule chemotherapeutics must cross one or more cellular membrane barriers to reach their biochemical targets. Owing to the relatively low solubility of chemotherapeutics in the lipid membrane environment, high doses are often required to achieve a therapeutic effect. The resulting syst...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 35(2019), 38 vom: 24. Sept., Seite 12532-12542
1. Verfasser: Trementozzi, Andrea N (VerfasserIn)
Weitere Verfasser: Imam, Zachary I, Mendicino, Morgan, Hayden, Carl C, Stachowiak, Jeanne C
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2019
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S. Liposomes Doxorubicin 80168379AG Propane T75W9911L6