OCT Angiography in Acute Posterior Multifocal Placoid Pigment Epitheliopathy

Copyright 2019, SLACK Incorporated.

Bibliographische Detailangaben
Veröffentlicht in:Ophthalmic surgery, lasers & imaging retina. - 2013. - 50(2019), 7 vom: 01. Juli, Seite 428-436
1. Verfasser: Furino, Claudio (VerfasserIn)
Weitere Verfasser: Shalchi, Zaid, Grassi, Maria Oliva, Cardoso, Joao N, Keane, Pearse A, Niro, Alfredo, Cicinelli, Maria Vittoria, Reibaldi, Michele, Boscia, Francesco, Alessio, Giovanni, Pavesio, Carlos
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2019
Zugriff auf das übergeordnete Werk:Ophthalmic surgery, lasers & imaging retina
Schlagworte:Case Reports Journal Article Research Support, Non-U.S. Gov't
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520 |a BACKGROUND AND OBJECTIVE: To describe retinal and choroidal findings in different stages of acute posterior multifocal placoid pigment epitheliopathy (APMPPE) 
520 |a PATIENTS AND METHODS: Retrospective, noncomparative case series studied by fundus biomicroscopy, fundus autofluorescence (FAF), fluorescein angiography (FA), indocyanine green angiography (ICGA), spectral-domain optical coherence tomographic (SD-OCT), and swept-source OCT angiography (SS-OCTA) 
520 |a RESULTS: Six eyes of three patients with bilateral APMPPE were included. FAF showed multifocal, branched patches of hyperautofluorescence with areas of hypoautofluorescence; FA disclosed early hypofluorescence, with late-phase hyperfluorescence; ICGA showed early and late-phase hypofluorescence. SD-OCT imaging revealed bilateral retinal thinning, external limiting membrane (ELM) disruption, and severe alteration of the photoreceptor-retinal pigment epithelium complex. SS-OCTA showed widespread multiple dark spots in the choriocapillaris in Cases 1 and 2. Rarefaction and voids in the vascular texture were also detected in the deep plexus, unlike in Case 3, where the lesions were smaller and earlier, suggesting that retina vasculature may be affected after the choriocapillaris obstruction 
520 |a CONCLUSIONS: APMPPE may result from a distinct focal ischemia in the choriocapillaris, and OCTA allowed the authors to localize exactly all the placoid lesions and monitor the areas of absent fluid signal. [Ophthalmic Surg Lasers Imaging Retina. 2019;50:428-436.] 
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650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
700 1 |a Shalchi, Zaid  |e verfasserin  |4 aut 
700 1 |a Grassi, Maria Oliva  |e verfasserin  |4 aut 
700 1 |a Cardoso, Joao N  |e verfasserin  |4 aut 
700 1 |a Keane, Pearse A  |e verfasserin  |4 aut 
700 1 |a Niro, Alfredo  |e verfasserin  |4 aut 
700 1 |a Cicinelli, Maria Vittoria  |e verfasserin  |4 aut 
700 1 |a Reibaldi, Michele  |e verfasserin  |4 aut 
700 1 |a Boscia, Francesco  |e verfasserin  |4 aut 
700 1 |a Alessio, Giovanni  |e verfasserin  |4 aut 
700 1 |a Pavesio, Carlos  |e verfasserin  |4 aut 
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