Size-Dependent Interaction of Amyloid β Oligomers with Brain Total Lipid Extract Bilayer-Fibrillation Versus Membrane Destruction

Amyloid β, Aβ(1-42), is a component of senile plaques present in the brain of Alzheimer's disease patients and one of the main suspects responsible for pathological consequences of the disease. Herein, we directly visualize the Aβ activity toward a brain-like model membrane and demonstrate that...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 35(2019), 36 vom: 10. Sept., Seite 11940-11949
1. Verfasser: Mrdenovic, Dusan (VerfasserIn)
Weitere Verfasser: Majewska, Marta, Pieta, Izabela S, Bernatowicz, Piotr, Nowakowski, Robert, Kutner, Wlodzimierz, Lipkowski, Jacek, Pieta, Piotr
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2019
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Amyloid beta-Peptides Lipid Bilayers