Structural knowledge or X-ray damage? A case study on xylose isomerase illustrating both

Xylose isomerase (XI) is an industrially important metalloprotein studied for decades. Its reaction mechanism has been postulated to involve movement of the catalytic metal cofactor to several different conformations. Here, a dose-dependent approach was used to investigate the radiation damage effec...

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Veröffentlicht in:Journal of synchrotron radiation. - 1994. - 26(2019), Pt 4 vom: 01. Juli, Seite 931-944
1. Verfasser: Taberman, Helena (VerfasserIn)
Weitere Verfasser: Bury, Charles S, van der Woerd, Mark J, Snell, Edward H, Garman, Elspeth F
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2019
Zugriff auf das übergeordnete Werk:Journal of synchrotron radiation
Schlagworte:Journal Article dose enzyme metalloprotein radiation damage specific structural damage structural pertubation xylose isomerase Amino Acids Aldose-Ketose Isomerases mehr... EC 5.3.1.- EC 5.3.1.5