Structural knowledge or X-ray damage? A case study on xylose isomerase illustrating both
Xylose isomerase (XI) is an industrially important metalloprotein studied for decades. Its reaction mechanism has been postulated to involve movement of the catalytic metal cofactor to several different conformations. Here, a dose-dependent approach was used to investigate the radiation damage effec...
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Bibliographische Detailangaben
Veröffentlicht in: | Journal of synchrotron radiation. - 1994. - 26(2019), Pt 4 vom: 01. Juli, Seite 931-944
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1. Verfasser: |
Taberman, Helena
(VerfasserIn) |
Weitere Verfasser: |
Bury, Charles S,
van der Woerd, Mark J,
Snell, Edward H,
Garman, Elspeth F |
Format: | Online-Aufsatz
|
Sprache: | English |
Veröffentlicht: |
2019
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Zugriff auf das übergeordnete Werk: | Journal of synchrotron radiation
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Schlagworte: | Journal Article
dose
enzyme
metalloprotein
radiation damage
specific structural damage
structural pertubation
xylose isomerase
Amino Acids
Aldose-Ketose Isomerases
mehr...
EC 5.3.1.-
EC 5.3.1.5 |