Arabidopsis defense mutant ndr1-1 displays accelerated development and early flowering mediated by the hormone gibberellic acid

Published by Elsevier B.V.

Détails bibliographiques
Publié dans:	Plant science : an international journal of experimental plant biology. - 1985. - 285(2019) vom: 17. Aug., Seite 200-213
Auteur principal:	Dhar, Nikhilesh (Auteur)
Autres auteurs:	Short, Dylan P G, Mamo, Bullo Erena, Corrion, Alex J, Wai, Ching Man, Anchieta, Amy, VanBuren, Robert, Day, Brad, Ajwa, Husein, Subbarao, Krishna V, Klosterman, Steven J
Format:	Article en ligne
Langue:	English
Publié:	2019
Accès à la collection:	Plant science : an international journal of experimental plant biology
Sujets:	Journal Article Arabidopsis NDR1 Defense and development Disease resistance Flowering time Gibberellic acid Salicylic acid Arabidopsis Proteins Gibberellins NDR1 protein, Arabidopsis plus... Plant Growth Regulators Transcription Factors gibberellic acid BU0A7MWB6L Salicylic Acid O414PZ4LPZ


LEADER	01000caa a22002652 4500
001	NLM298204444
003	DE-627
005	20250225114710.0
007	cr uuu---uuuuu
008	231225s2019 xx \|\|\|\|\|o 00\| \|\|eng c
024	7		\|a 10.1016/j.plantsci.2019.04.006 \|2 doi
028	5	2	\|a pubmed25n0993.xml
035			\|a (DE-627)NLM298204444
035			\|a (NLM)31203885
035			\|a (PII)S0168-9452(19)30042-1
040			\|a DE-627 \|b ger \|c DE-627 \|e rakwb
041			\|a eng
100	1		\|a Dhar, Nikhilesh \|e verfasserin \|4 aut
245	1	0	\|a Arabidopsis defense mutant ndr1-1 displays accelerated development and early flowering mediated by the hormone gibberellic acid
264		1	\|c 2019
336			\|a Text \|b txt \|2 rdacontent
337			\|a ƒaComputermedien \|b c \|2 rdamedia
338			\|a ƒa Online-Ressource \|b cr \|2 rdacarrier
500			\|a Date Completed 13.08.2019
500			\|a Date Revised 30.09.2020
500			\|a published: Print-Electronic
500			\|a Citation Status MEDLINE
520			\|a Published by Elsevier B.V.
520			\|a NONRACE-SPECIFIC DISEASE RESISTANCE (NDR1) is a widely characterized gene that plays a key role in defense against multiple bacterial, fungal, oomycete and nematode plant pathogens. NDR1 is required for activation of resistance by multiple NB and LRR-containing (NLR) protein immune sensors and contributes to basal defense. The role of NDR1 in positively regulating salicylic acid (SA)-mediated plant defense responses is well documented. However, ndr1-1 plants flower earlier and show accelerated development in comparison to wild type (WT) Arabidopsis plants, indicating that NDR1 is a negative regulator of flowering and growth. Exogenous application of gibberellic acid (GA) further accelerates the early flowering phenotype in ndr1-1 plants, while the GA biosynthesis inhibitor paclobutrazol attenuated the early flowering phenotype of ndr1-1, but not to WT levels, suggesting partial resistance to paclobutrazol and enhanced GA response in ndr1-1 plants. Mass spectroscopy analyses confirmed that ndr1-1 plants have 30-40% higher levels of GA3 and GA4, while expression of various GA metabolic genes and major flowering regulatory genes is also altered in the ndr1-1 mutant. Taken together this study provides evidence of crosstalk between the ndr1-1-mediated defense and GA-regulated developmental programs in plants
650		4	\|a Journal Article
650		4	\|a Arabidopsis NDR1
650		4	\|a Defense and development
650		4	\|a Disease resistance
650		4	\|a Flowering time
650		4	\|a Gibberellic acid
650		4	\|a Salicylic acid
650		7	\|a Arabidopsis Proteins \|2 NLM
650		7	\|a Gibberellins \|2 NLM
650		7	\|a NDR1 protein, Arabidopsis \|2 NLM
650		7	\|a Plant Growth Regulators \|2 NLM
650		7	\|a Transcription Factors \|2 NLM
650		7	\|a gibberellic acid \|2 NLM
650		7	\|a BU0A7MWB6L \|2 NLM
650		7	\|a Salicylic Acid \|2 NLM
650		7	\|a O414PZ4LPZ \|2 NLM
700	1		\|a Short, Dylan P G \|e verfasserin \|4 aut
700	1		\|a Mamo, Bullo Erena \|e verfasserin \|4 aut
700	1		\|a Corrion, Alex J \|e verfasserin \|4 aut
700	1		\|a Wai, Ching Man \|e verfasserin \|4 aut
700	1		\|a Anchieta, Amy \|e verfasserin \|4 aut
700	1		\|a VanBuren, Robert \|e verfasserin \|4 aut
700	1		\|a Day, Brad \|e verfasserin \|4 aut
700	1		\|a Ajwa, Husein \|e verfasserin \|4 aut
700	1		\|a Subbarao, Krishna V \|e verfasserin \|4 aut
700	1		\|a Klosterman, Steven J \|e verfasserin \|4 aut
773	0	8	\|i Enthalten in \|t Plant science : an international journal of experimental plant biology \|d 1985 \|g 285(2019) vom: 17. Aug., Seite 200-213 \|w (DE-627)NLM098174193 \|x 1873-2259 \|7 nnns
773	1	8	\|g volume:285 \|g year:2019 \|g day:17 \|g month:08 \|g pages:200-213
856	4	0	\|u http://dx.doi.org/10.1016/j.plantsci.2019.04.006 \|3 Volltext
912			\|a GBV_USEFLAG_A
912			\|a SYSFLAG_A
912			\|a GBV_NLM
912			\|a GBV_ILN_350
951			\|a AR
952			\|d 285 \|j 2019 \|b 17 \|c 08 \|h 200-213