CEP3 levels affect starvation-related growth responses of the primary root

CEP3 levels affect starvation-related growth responses of the primary root

© The Author(s) 2019. Published by Oxford University Press on behalf of the Society for Experimental Biology.

Bibliographische Detailangaben
Veröffentlicht in:Journal of experimental botany. - 1985. - 70(2019), 18 vom: 24. Sept., Seite 4763-4774
1. Verfasser: Delay, Christina (VerfasserIn)
Weitere Verfasser: Chapman, Kelly, Taleski, Michael, Wang, Yaowei, Tyagi, Sonika, Xiong, Yan, Imin, Nijat, Djordjevic, Michael A
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2019
Zugriff auf das übergeordnete Werk:Journal of experimental botany
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Amino acid catabolism CEP CEPR1 TOR carbon limitation cell cycle nitrogen limitation peptide hormone mehr... primary root growth AT2G23440 protein, Arabidopsis Arabidopsis Proteins CEPR1 protein, Arabidopsis Intercellular Signaling Peptides and Proteins Receptors, Peptide
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520 |a CEPs (C-TERMINALLY ENCODED PEPTIDEs) inhibit Arabidopsis primary root growth by unknown mechanisms. We investigated how CEP3 levels control primary root growth. CEP3 peptide application decreased cell division, S-phase cell number, root meristematic cell number, and meristem zone (MZ) size in a dose- and CEP RECEPTOR1-dependent manner. Grafting showed that CEP3-dependent growth inhibition requires root and shoot CEPR1. CEP3 induced mitotic quiescence in MZ cells significantly faster than that induced by nutrient limitation alone. CEP3 also inhibited the restoration of S-phase to mitotically quiescence cells by nutrient resupply without quantitatively reducing TARGET OF RAPAMYCIN (TOR) kinase activity. In contrast, cep3-1 had an increased meristem size and S-phase cell number under nitrogen (N)-limited conditions, but not under N-sufficient conditions. Furthermore, cep3-1 meristematic cells remained in S-phase longer than wild-type cells during a sustained carbon (C) and N limitation. RNA sequencing showed that CEP3 peptide down-regulated genes involved in S-phase entry, cell wall and ribosome biogenesis, DNA replication, and meristem expansion, and up-regulated genes involved in catabolic processes and proteins and peptides that negatively control meristem expansion and root growth. Many of these genes were reciprocally regulated in cep3-1. The results suggest that raising CEP3 induces starvation-related responses that curtail primary root growth under severe nutrient limitation 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
650 4 |a Amino acid catabolism 
650 4 |a CEP 
650 4 |a CEPR1 
650 4 |a TOR 
650 4 |a carbon limitation 
650 4 |a cell cycle 
650 4 |a nitrogen limitation 
650 4 |a peptide hormone 
650 4 |a primary root growth 
650 7 |a AT2G23440 protein, Arabidopsis  |2 NLM 
650 7 |a Arabidopsis Proteins  |2 NLM 
650 7 |a CEPR1 protein, Arabidopsis  |2 NLM 
650 7 |a Intercellular Signaling Peptides and Proteins  |2 NLM 
650 7 |a Receptors, Peptide  |2 NLM 
700 1 |a Chapman, Kelly  |e verfasserin  |4 aut 
700 1 |a Taleski, Michael  |e verfasserin  |4 aut 
700 1 |a Wang, Yaowei  |e verfasserin  |4 aut 
700 1 |a Tyagi, Sonika  |e verfasserin  |4 aut 
700 1 |a Xiong, Yan  |e verfasserin  |4 aut 
700 1 |a Imin, Nijat  |e verfasserin  |4 aut 
700 1 |a Djordjevic, Michael A  |e verfasserin  |4 aut 
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773 1 8 |g volume:70  |g year:2019  |g number:18  |g day:24  |g month:09  |g pages:4763-4774 
856 4 0 |u http://dx.doi.org/10.1093/jxb/erz270  |3 Volltext 
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