A Case of Renal Cell Carcinoma Choroidal Metastasis Diagnosed from Vision Disorders

A 69-year-old male with the complaint of a cough was referred to our hospital from a clinic where he was found to have simultaneous metastases of the left kidney tumor. We performed left cytoreductive nephrectomy, and administered sunitinib after the surgery. The first line treatment was not effecti...

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Détails bibliographiques
Publié dans:Hinyokika kiyo. Acta urologica Japonica. - 1962. - 65(2019), 2 vom: 18. Feb., Seite 33-37
Auteur principal: Imai, Yu (Auteur)
Autres auteurs: Matsuura, Taishi, Hisakane, Akira, Moritake, Jun, Bando, Shigehiro, Yamada, Hiroki, Kiyota, Hiroshi, Iida, Kie, Egawa, Shin
Format: Article en ligne
Langue:Japanese
Publié: 2019
Accès à la collection:Hinyokika kiyo. Acta urologica Japonica
Sujets:Case Reports Journal Article
Description
Résumé:A 69-year-old male with the complaint of a cough was referred to our hospital from a clinic where he was found to have simultaneous metastases of the left kidney tumor. We performed left cytoreductive nephrectomy, and administered sunitinib after the surgery. The first line treatment was not effective. Then we changed the therapeutic agent to pazopanib as the second line treatment. Lung and lymph node metastases gradually shrunk, but he developed right vision disorders and was diagnosed with bilateral metastatic retinal tumors. First, irradiation to the right eye was performed while discontinuing pazopanib. Sudden treatment withdrawal caused his general condition to worsen temporally, but irradiation could be continued by resuming administration of pazopanib. As a consequence, the progression of the visual field disorder was suppressed by the additional ophthalmologic treatment. Renal cell carcinoma choroidal metastases are rare, but we need to consider them when the patient has vision disorders
Description:Date Completed 10.06.2019
Date Revised 13.06.2019
published: Print
Citation Status MEDLINE
ISSN:0018-1994
DOI:10.14989/ActaUrolJap_65_2_33