Synthesis and Avidin Binding of Ruthenium Complexes Functionalized with a Light-Cleavable Free Biotin Moiety

In this work the synthesis, photochemistry, and streptavidin interaction of new [Ru(tpy)(bpy)(SRR')](PF6)2 complexes where the R' group contains a free biotin ligand, are described. Two different ligands SRR' were investigated: An asymmetric ligand 1 where the Ru-bound thioether is a...

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Veröffentlicht in:European journal of inorganic chemistry. - 1998. - 2018(2018), 37 vom: 09. Okt., Seite 4117-4124
1. Verfasser: Siewert, Bianka (VerfasserIn)
Weitere Verfasser: Langerman, Michiel, Pannwitz, Andrea, Bonnet, Sylvestre
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2018
Zugriff auf das übergeordnete Werk:European journal of inorganic chemistry
Schlagworte:Journal Article Antitumor agents Biotin Photochemistry Ruthenium Streptavidin Synthesis design Thioethers