Intravitreal Anti-Vascular Endothelial Growth Factor Injections for Macular Edema Associated With Central Retinal Vein Occlusion in Patients Age 40 Years or Younger

Copyright 2019, SLACK Incorporated.

Bibliographische Detailangaben
Veröffentlicht in:Ophthalmic surgery, lasers & imaging retina. - 2013. - 50(2019), 4 vom: 01. Apr., Seite e96-e104
1. Verfasser: Gao, Xinxiao (VerfasserIn)
Weitere Verfasser: Obeid, Anthony, Aderman, Christopher M, Ali, Ferhina S, Vander, James F, Hsu, Jason, Ho, Allen C
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2019
Zugriff auf das übergeordnete Werk:Ophthalmic surgery, lasers & imaging retina
Schlagworte:Journal Article Angiogenesis Inhibitors Bevacizumab 2S9ZZM9Q9V Receptors, Vascular Endothelial Growth Factor EC 2.7.10.1
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245 1 0 |a Intravitreal Anti-Vascular Endothelial Growth Factor Injections for Macular Edema Associated With Central Retinal Vein Occlusion in Patients Age 40 Years or Younger 
264 1 |c 2019 
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500 |a Date Revised 17.12.2019 
500 |a published: Print 
500 |a Citation Status MEDLINE 
520 |a Copyright 2019, SLACK Incorporated. 
520 |a BACKGROUND AND OBJECTIVE: To determine the efficacy of anti-vascular endothelial growth factor (VEGF) therapy for macular edema due to central retinal vein occlusion (CRVO) in younger adults 
520 |a PATIENTS AND METHODS: The outcomes of CRVO patients age 40 years or younger with baseline logarithm of the minimum angle of resolution (logMAR) visual acuity (VA) between 1.30 (20/400 Snellen equivalent) and 0.30 (20/40 Snellen equivalent) and central retinal thickness (CRT) greater than 250 μm were reviewed. VA and CRT were measured at baseline and months 1, 3, 6, and 12 
520 |a RESULTS: Seventeen eyes of 17 young CRVO patients were included in this study. The logMAR VA improved significantly from 0.64 (20/87 Snellen equivalent) to 0.14 (20/28 Snellen equivalent) 12 months following treatments (P < .001). The CRT decreased from 619 μm ± 238 μm at baseline to 290 μm ± 34 μm at 12 months (P < .001) 
520 |a CONCLUSION: Anti-VEGF injections appear to be effective for macular edema regression and vision improvement in younger adults with CRVO over 12 months of follow-up. [Ophthalmic Surg Lasers Imaging Retina. 2019;50:e96-e104.] 
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650 7 |a Receptors, Vascular Endothelial Growth Factor  |2 NLM 
650 7 |a EC 2.7.10.1  |2 NLM 
700 1 |a Obeid, Anthony  |e verfasserin  |4 aut 
700 1 |a Aderman, Christopher M  |e verfasserin  |4 aut 
700 1 |a Ali, Ferhina S  |e verfasserin  |4 aut 
700 1 |a Vander, James F  |e verfasserin  |4 aut 
700 1 |a Hsu, Jason  |e verfasserin  |4 aut 
700 1 |a Ho, Allen C  |e verfasserin  |4 aut 
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