Tetraazamacrocyclic derivatives and their metal complexes as antileishmanial leads

A total of 44 bis-aryl-monocyclic polyamines, monoaryl-monocyclic polyamines and their transition metal complexes were prepared, chemically characterized, and screened in vitro against the Leishmania donovani promastigotes, axenic amastigotes and intracellular amastigotes in THP1 cells. The IC50 and...

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Veröffentlicht in:Polyhedron. - 1997. - 163(2019) vom: 01. Mai, Seite 42-53
1. Verfasser: Hubin, Timothy J (VerfasserIn)
Weitere Verfasser: Walker, Ashlie N, Davilla, Dustin J, Freeman, TaRynn N Carder, Epley, Brittany M, Hasley, Travis R, Amoyaw, Prince N A, Jain, Surendra, Archibald, Stephen J, Prior, Timothy J, Krause, Jeanette A, Oliver, Allen G, Tekwani, Babu L, Khan, M Omar F
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2019
Zugriff auf das übergeordnete Werk:Polyhedron
Schlagworte:Journal Article Cyclen antileishmanial drug lead cyclam metal complexes polyamine