Tetraazamacrocyclic derivatives and their metal complexes as antileishmanial leads
A total of 44 bis-aryl-monocyclic polyamines, monoaryl-monocyclic polyamines and their transition metal complexes were prepared, chemically characterized, and screened in vitro against the Leishmania donovani promastigotes, axenic amastigotes and intracellular amastigotes in THP1 cells. The IC50 and...
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Bibliographische Detailangaben
Veröffentlicht in: | Polyhedron. - 1997. - 163(2019) vom: 01. Mai, Seite 42-53
|
1. Verfasser: |
Hubin, Timothy J
(VerfasserIn) |
Weitere Verfasser: |
Walker, Ashlie N,
Davilla, Dustin J,
Freeman, TaRynn N Carder,
Epley, Brittany M,
Hasley, Travis R,
Amoyaw, Prince N A,
Jain, Surendra,
Archibald, Stephen J,
Prior, Timothy J,
Krause, Jeanette A,
Oliver, Allen G,
Tekwani, Babu L,
Khan, M Omar F |
Format: | Online-Aufsatz
|
Sprache: | English |
Veröffentlicht: |
2019
|
Zugriff auf das übergeordnete Werk: | Polyhedron
|
Schlagworte: | Journal Article
Cyclen
antileishmanial drug lead
cyclam
metal complexes
polyamine |