Loss to Follow-Up in Patients With Retinal Vein Occlusion Undergoing Intravitreal Anti-VEGF Injections

Copyright 2019, SLACK Incorporated.

Bibliographische Detailangaben
Veröffentlicht in:Ophthalmic surgery, lasers & imaging retina. - 2013. - 50(2019), 3 vom: 01. März, Seite 159-166
1. Verfasser: Gao, Xinxiao (VerfasserIn)
Weitere Verfasser: Obeid, Anthony, Adam, Murtaza K, Hyman, Leslie, Ho, Allen C, Hsu, Jason
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2019
Zugriff auf das übergeordnete Werk:Ophthalmic surgery, lasers & imaging retina
Schlagworte:Journal Article Angiogenesis Inhibitors Recombinant Fusion Proteins Vascular Endothelial Growth Factor A aflibercept 15C2VL427D Bevacizumab 2S9ZZM9Q9V Receptors, Vascular Endothelial Growth Factor EC 2.7.10.1 mehr... Ranibizumab ZL1R02VT79
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100 1 |a Gao, Xinxiao  |e verfasserin  |4 aut 
245 1 0 |a Loss to Follow-Up in Patients With Retinal Vein Occlusion Undergoing Intravitreal Anti-VEGF Injections 
264 1 |c 2019 
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500 |a CommentIn: Eye (Lond). 2023 Feb;37(3):453-458. - PMID 35132210 
500 |a Citation Status MEDLINE 
520 |a Copyright 2019, SLACK Incorporated. 
520 |a BACKGROUND AND OBJECTIVE: To identify the proportion of patients with retinal vein occlusion (RVO) with loss to follow-up (LTFU) along with potential risk factors after receiving an intravitreal anti-vascular endothelial growth factor (VEGF) injection 
520 |a PATIENTS AND METHODS: A retrospective review based on billing codes was performed from January 1, 2012, to January 1, 2017. LTFU was defined as no office visit within 12 months following an intravitreal injection. Potential risk factors for LTFU were screened using univariate analysis for inclusion in a final multivariate logistic regression model 
520 |a RESULTS: A total of 3,400 unique patients with RVO with macular edema met the study inclusion criteria. Of these, 863 patients (25.4%) were LTFU. Rates of LTFU varied based on race / ethnicity, age, RVO type, distance from clinic, insurance status, and regional average adjusted gross income. In the multivariate analysis, patients with LTFU were more likely to be black (odds ratio [OR] = 1.37), Hispanic (OR = 2.37), and living more than 20 miles away from clinic (OR = 1.47). Patients who were 65 to 80 years old (OR = 0.71) and those with branch retinal vein occlusion (OR = 0.70) were less likely to be LTFU. Subgroup analysis showed that patients with baseline visual acuity better than 20/50 were also less likely to be LTFU 
520 |a CONCLUSIONS: Approximately one in four patients did not return for a year or more after receiving an intravitreal injection for RVO. Given the importance of ongoing therapy to prevent vision loss, these "real-world" findings are of significant concern. [Ophthalmic Surg Lasers Imaging Retina. 2019;50:159-166.] 
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650 7 |a Angiogenesis Inhibitors  |2 NLM 
650 7 |a Recombinant Fusion Proteins  |2 NLM 
650 7 |a Vascular Endothelial Growth Factor A  |2 NLM 
650 7 |a aflibercept  |2 NLM 
650 7 |a 15C2VL427D  |2 NLM 
650 7 |a Bevacizumab  |2 NLM 
650 7 |a 2S9ZZM9Q9V  |2 NLM 
650 7 |a Receptors, Vascular Endothelial Growth Factor  |2 NLM 
650 7 |a EC 2.7.10.1  |2 NLM 
650 7 |a Ranibizumab  |2 NLM 
650 7 |a ZL1R02VT79  |2 NLM 
700 1 |a Obeid, Anthony  |e verfasserin  |4 aut 
700 1 |a Adam, Murtaza K  |e verfasserin  |4 aut 
700 1 |a Hyman, Leslie  |e verfasserin  |4 aut 
700 1 |a Ho, Allen C  |e verfasserin  |4 aut 
700 1 |a Hsu, Jason  |e verfasserin  |4 aut 
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