Cationic Amphiphiles with Specificity against Gram-Positive and Gram-Negative Bacteria : Chemical Composition and Architecture Combat Bacterial Membranes

Small-molecule cationic amphiphiles (CAms) were designed to combat the rapid rise in drug-resistant bacteria. CAms were designed to target and compromise the structural integrity of bacteria membranes, leading to cell rupture and death. Discrete structural features of CAms were varied, and structure...

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Bibliographische Detailangaben

Veröffentlicht in:	Langmuir : the ACS journal of surfaces and colloids. - 1999. - 35(2019), 16 vom: 23. Apr., Seite 5557-5567
1. Verfasser:	Moretti, Alysha (VerfasserIn)
Weitere Verfasser:	Weeks, Richard M, Chikindas, Michael, Uhrich, Kathryn E
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2019
Zugriff auf das übergeordnete Werk:	Langmuir : the ACS journal of surfaces and colloids
Schlagworte:	Journal Article Research Support, N.I.H., Extramural Anti-Bacterial Agents Cations Surface-Active Agents