Chronic toxicity and biochemical response of Apis cerana cerana (Hymenoptera : Apidae) exposed to acetamiprid and propiconazole alone or combined

Acetamiprid and ergosterol-inhibiting fungicide (EBI) are frequently applied to many flowering plants, while honey bees are pollinating agents or pollinators of the flowers. Hence honey bees are often exposed to these pesticides. But until now, the effects of theses combinations at field-realistic d...

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Veröffentlicht in:Ecotoxicology (London, England). - 1992. - 28(2019), 4 vom: 12. Mai, Seite 399-411
1. Verfasser: Han, Wensu (VerfasserIn)
Weitere Verfasser: Yang, Yemeng, Gao, Jinglin, Zhao, Dongxiang, Ren, Chengcai, Wang, Shijie, Zhao, Shan, Zhong, Yihai
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2019
Zugriff auf das übergeordnete Werk:Ecotoxicology (London, England)
Schlagworte:Journal Article Apis cerana cerana Detoxification enzymes Physiological effects Synergistic mortality Biomarkers Fungicides, Industrial Insecticides Neonicotinoids Triazoles mehr... propiconazole 142KW8TBSR acetamiprid 5HL5N372P0
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520 |a Acetamiprid and ergosterol-inhibiting fungicide (EBI) are frequently applied to many flowering plants, while honey bees are pollinating agents or pollinators of the flowers. Hence honey bees are often exposed to these pesticides. But until now, the effects of theses combinations at field-realistic doses on honey bee health have been poorly investigated. In this study, we explore the synergistic mortality and some physiological effects in surviving honey bees after chronic oral exposure to acetamiprid and/or propiconazole in the laboratory. The results indicated that chronic combined exposure to acetamiprid and propiconazole produced a significant synergistic effect on mortality both for newly emerged bees (50% mortality in 7.2 days) and forager bees (50% mortality in 4.8 days). Honey bee weight of newly emerged bees was decreased after feeding food with a field concentration of acetamiprid and propiconazole, alone or combined for 10 days. Combination of acetamiprid and propiconazole also modulated the activities of P450s, GST and CAT in newly emerged bees and forager bees than either alone, but neither pesticide affected the activity of AChE. These results show that chronic combined exposure to pesticides of relatively low toxicity may caused severely physiological disruptions that could be potentially damaging for the honey bees 
650 4 |a Journal Article 
650 4 |a Apis cerana cerana 
650 4 |a Detoxification enzymes 
650 4 |a Physiological effects 
650 4 |a Synergistic mortality 
650 7 |a Biomarkers  |2 NLM 
650 7 |a Fungicides, Industrial  |2 NLM 
650 7 |a Insecticides  |2 NLM 
650 7 |a Neonicotinoids  |2 NLM 
650 7 |a Triazoles  |2 NLM 
650 7 |a propiconazole  |2 NLM 
650 7 |a 142KW8TBSR  |2 NLM 
650 7 |a acetamiprid  |2 NLM 
650 7 |a 5HL5N372P0  |2 NLM 
700 1 |a Yang, Yemeng  |e verfasserin  |4 aut 
700 1 |a Gao, Jinglin  |e verfasserin  |4 aut 
700 1 |a Zhao, Dongxiang  |e verfasserin  |4 aut 
700 1 |a Ren, Chengcai  |e verfasserin  |4 aut 
700 1 |a Wang, Shijie  |e verfasserin  |4 aut 
700 1 |a Zhao, Shan  |e verfasserin  |4 aut 
700 1 |a Zhong, Yihai  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Ecotoxicology (London, England)  |d 1992  |g 28(2019), 4 vom: 12. Mai, Seite 399-411  |w (DE-627)NLM098212214  |x 1573-3017  |7 nnns 
773 1 8 |g volume:28  |g year:2019  |g number:4  |g day:12  |g month:05  |g pages:399-411 
856 4 0 |u http://dx.doi.org/10.1007/s10646-019-02030-4  |3 Volltext 
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