Binding of SV40's Viral Capsid Protein VP1 to Its Glycosphingolipid Receptor GM1 Induces Negative Membrane Curvature : A Molecular Dynamics Study

The binding of the pentameric capsid protein VP1 of simian virus 40 to its glycosphingolipid receptor GM1 is a key step for the entry of the virus into the host cell. Recent experimental studies have shown that the interaction of variants of soluble VP1 pentamers with giant unilamellar vesicles comp...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 35(2019), 9 vom: 05. März, Seite 3534-3544
1. Verfasser: Kociurzynski, Raisa (VerfasserIn)
Weitere Verfasser: Beck, Sophie D, Bouhon, Jean-Baptiste, Römer, Winfried, Knecht, Volker
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2019
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Capsid Proteins Lipid Bilayers Phosphatidylcholines Receptors, Cell Surface VP1 protein, polyomavirus ganglioside receptor G(M1) Ganglioside 37758-47-7 mehr... Cholesterol 97C5T2UQ7J 1,2-oleoylphosphatidylcholine EDS2L3ODLV